clindamycin


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Related to clindamycin: metronidazole, Clindamycin phosphate

clindamycin

 [klin″dah-mi´sin]
1. a semisynthetic antibiotic that is a derivative of lincomycin; used to treat gram-positive penicillin-resistant infections.
2. a semisynthetic derivative of lincomycin used systemically, topically, and vaginally as an antibacterial, primarily against gram-positive bacteria; used also as the hydrochloride and phosphate salts and as the hydrochloride salt of the ester of clindamycin and palmitic acid (clindamycin palmitate hydrochloride).

clindamycin

(klĭn′də-mī′sĭn)
n.
A semisynthetic antibiotic, C18H33ClN2O5S, derived from lincomycin and active against gram-positive bacteria.

clindamycin

Infectious disease An antibiotic combined with pyrimethamine to treat and prevent toxoplasmosis, PCP and, topically, for acne vulgaris Adverse effects Diarrhea, dysgeusia. See AIDS.

clindamycin

An antibiotic drug that penetrates well into bone to treat OSTEOMYELITIS. The drug is on the WHO official list. Brand names are Dalacin C and, for external use, Dalacin T.
References in periodicals archive ?
After the patient was switched to pyrimethamine plus clindamycin, his renal function persistently worsened, and a drug-induced lymphocyte stimulation test suggested that pyrimethamine was responsible for the acute renal failure.
Clindamycin is an antibiotic that stops the growth of acne-causing bacteria.
The United States Food and Drug Administration (FDA) has approved the marketing of India-based Zydus Cadila's Clindamycin Phosphate and Benzoyl Peroxide Gel, it was reported on Monday.
acnes.9-11 To treat mild to moderate acne, it can be used alone or in combination with topical antibiotics and topical retinoids.12 Clindamycin improves acne by reducing the levels of P.
This type of inducible Clindamycin resistance cannot be detected by standard Kirby-Bauer disk diffusion method, broth microdilution testing, automated susceptibility testing devices or Epsilometer test.
Conclusion: An association of clindamycin and ciprofloxacin resistance with CA S.
In a population-based cohort study in 139,938 liveborn singletons, there was an 81% increased risk of ventricular/septal defect (adjusted odds ratio, 1.81) associated with clindamycin exposure during the first trimester, compared with no exposure.
At follow-up 7-10 days following the conclusion of treatment, the rates of clinical cure were 83.1% with clindamycin and 81.7% with TMP-SMX, both significantly greater than the 68.9% cure rate with placebo (P less than .001 for both comparisons).
They found that clindamycin and TMP/SMX were equally effective in adults, while clindamycin in children had a slightly higher cure rate in children and more frequently prevented recurrence of infection.
"Daptomycin is a suitable once-daily alternative to vancomycin or clindamycin in the pediatric setting, particularly for suspected or confirmed MRSA [methicillin-resistant Staphylococcus aureus] infections," the investigators concluded.
All isolates were tested for ampicillin (10 [micro]g), cefotaxime, ceftriaxone (30[micro]g), clindamycin (2 [micro]g), chloramphenicol (30 [micro]g), erythromycin (15 [micro]g), levofloxacin (5 [micro]g), penicillin (10 unit), vancomycin (30[micro]g),kanamycin (30[micro]g),streptomycin (10 [micro]g),gentamycin (30 [micro]g) and tetracycline (30 [micro]g).
Treatment requires surgical debridement of necrotic tissue along with antimicrobials, typically including penicillin and clindamycin. The addition of clindamycin to penicillin for the treatment of streptococcal TSS is recommended as adjunctive therapy after immediate source control due to its toxin suppression activity [2].