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an antihistamine with sedative and anticholinergic effects; used as the fumarate salt in the treatment of nasal, eye, and skin manifestations of allergic reactions, including allergic rhinitis, conjunctivitis, and itching, and also as an ingredient in cough and cold preparations, administered orally.
clemastine/clem·as·tine/ (klem´as-tēn) an antihistamine with anticholinergic and sedative effects, used as the fumarate salt.
indications It is prescribed in the treatment of symptoms of allergic rhinitis, pruritus, or conjunctivitis.
contraindications Use by lactating mothers or those undergoing monamine oxidase inhibitor therapy or having known sensitivity to this drug or other antihistamines is contraindicated. It is also contraindicated with narrow-angle glaucoma, asthma, symptomatic prostatic hypertrophy, and bladder-neck destruction.
adverse effects Among the most serious adverse reactions are hypersensitivity, skin rash, and tachycardia. Transient drowsiness commonly occurs.
clemastineA sedating antihistamine and anticholinergic used for managing allergic rhinitis and hay fever.
CNS depression or stimulation; the latter is more common in children and may be accompanied by excitement, hallucinations, ataxia, incoordination, spasms, athetosis, hyperthermia, cyanosis, hyperreflexia and cardiorespiratory arrest.