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leukoencephalopathy with vanishing white matter

A leukodystrophy of childhood onset (OMIM:603896) characterised by progressive cerebellar ataxia, spasticity, variable optic atrophy and relatively preserved mental abilities. Leukodystrophy with vanishing white matter is usually slowly progressive, but may undergo rapid deterioration after fever or minor head trauma. Clinical variants include a severe, early-onset form seen among the Cree and Chippewayan populations of Quebec and Manitoba (Cree leukoencephalopathy), and a milder form affecting females who survive to adolescence and exhibit ovarian dysfunction (ovarioleukodystrophy).

Molecular pathology
Defects in EIF2B1, which encodes a subunit of eukaryotic translation initiation factor 2B (EIF2B), an essential regulator of protein synthesis, are a cause of leukodystrophy with vanishing white matter.

Cle

total elimination clearance.

Patient discussion about Cle

Q. Cn barret esophagous be cured? I was diagnosed with barretts esophagus several years ago, and so far keeps on the routine follow up. I met some other guy with same condition and he told after his doctor prescribed him with some anti-reflux meds, in the last endoscopy they found normal esophagus, and that he thinks he's now cured. Is that possible?

A. Anti-reflux treatment may lower the risk of cancer a little, but it won't cure it, so there's still a need for refular follow-up.

More discussions about Cle
References in periodicals archive ?
Clef is an example of what's called "two-factor authentication" which combines something you know (your password or PIN) with something you have (in this case, your phone)
Each school had a multi-tiered choral program with auditioned mixed ensembles, non-auditioned mixed ensembles and at least one treble clef choir.
Frank Lynch, former boss of Glasgow's legendary Apollo Theatre, flew home from South Carolina to receive the Tartan Clef for Industry, an award sponsored by the Sunday Mail.
Cello: In older editions, cello parts in treble clef are sometimes written an octave higher than sounding pitch.
Moving beyond semiotics, the second preliminary theoretical assumption pertains to what Barthes perceives as a problematic generic categorization of the roman a clefs, or the "key novel," in which actual persons appear as fictitious characters, and is closely aligned with his subsequent discussion of the photographs.
At the first entry of any part whose clef has been altered Cessac includes the original clef at the beginning of the staff, thereby allowing us to make intelligent choices concerning vocal and instrumental scoring -- given the scarcity of specific directions.
roman a clefplural romans a clef French, literally, novel with a key
Lionel Richie is expected to be the centre of attention at the ceremony in London, where he will be presented with the O2 Silver Clef Award.
Similar to a regular deck of cards in which each card contains a suit and a number value, each Notolio card contains a suit--eighth, quarter, half or whole note--plus a treble clef note or a letter from the music alphabet.
The singer - who has had a new chapter in his career thanks to three series as a coach on BBC1's The Voice - will be given the prize at the annual O2 Silver Clef Awards next month.
Santos is the founder of Dubai Concierge Group and the first Les Clef d'Or member in Qatar.
Despite a few minor editing glitches (random clef change in horn four, some confusing notation in mm.