clear cell

1. a cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;

2. any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.

Farlex Partner Medical Dictionary © Farlex 2012

clear cell

(klîr)

A cell, especially a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cytoplasm appears clear histologically.

A finely vacuolated, cholesterol-filled cell with central dark nuclei, which is arranged in clusters and located in the midzone or zona fasciculata of the adrenal cortex. Clear cells are the major reservoir for glucocorticoid and sex hormone production when the adrenal gland is stressed

clear cell

(klēr sel)

1. A cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;

2. Any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.

Medical Dictionary for the Health Professions and Nursing © Farlex 2012

References in periodicals archive ?

Squamous cell carcinoma in situ arising within clear cell acanthoma.

Clear Cell Acanthoma in an Unexpected Location

This differential is further aggravated by the existence of the so-called eosinophilic or oncocytic subtypes of clear cell renal cell carcinoma and chromophobe renal cell carcinoma [4], particularly when secondary regressive tissue alterations such as pseudocystic change and necrosis occur.

MicroRNAs as Urinary Biomarker for Oncocytoma

She had a past medical history of right RCC, clear cell carcinoma subtype with bilateral adrenal metastasis (T3b, N0, and M1) diagnosed in May 2006.

A Rare Case of Metastasis to the Thyroid Gland from Renal Clear Cell Carcinoma 11 Years after Nephrectomy and Concurrent Primary Esophageal Carcinoma

Clear cell papulosis (CCP) is a benign childhood skin condition.

Clear Cell Papulosis: A Rare Pediatric Dermatosis

Sex cord-stromal tumors and clear cell carcinoma can show solid growth patterns with diffuse clear cell morphology which resemble seminoma [7] and differentiating between the disorders can be challenging.

Synchronous Leydig Cell Tumor and Seminoma in the Ipsilateral Testis

Immunohistostaining showed that hepatocyte nuclear factor-1beta (HNF-1[beta]) was positive, p53 was negative, ER was negative, and progesterone receptor (PgR) was focally positive, indicating that most of the tumor presented the features of clear cell adenocarcinoma (Figure 5).

Clear Cell Adenocarcinoma Arising from Endometriosis in the Groin: Wide Resection and Reconstruction with a Fascia Lata Tensor Muscle Skin Flap

Mullerian neoplasms of the urinary system are a rare entity of neoplasms that are subdivided into Clear Cell Carcinoma (CCC) and Endometrioid Carcinoma.

A Rare Case of Clear Cell Carcinoma, Mullerian Type in the Renal Pelvis of a 21-Year-Old Woman

The histopathology of the RCC was of a clear cell type (TNM stage pT1 NX G2 L0 V0 R0 M0) and Fuhrmann grade 2 without any sarcomatoid aspect and was treated with a nephrectomy.

Metastases to Both Parotid Glands Six and Twelve Years after Resection of Renal Cell Carcinoma

Of 51 nephrectomy specimens, 46/51 was RCC; 5/51 were others which include solitary fibrous tumour, clear cell sarcoma, angiomyolipoma and oncocytoma.

HISTOPATHOLOGICAL ANALYSIS OF RENAL TUMOURS--A TWO YEAR STUDY FROM A TERTIARY CARE CENTRE

Liam Debbage, 31, was diagnosed with clear cell sarcoma 16 months ago after he injured his shoulder playing squash.

Work colleagues' gift of hope to cancer fighter

Large clear cell adenoma of the parathyroid in a patient with MEN-1 syndrome: ultrastructural study of the tumour exhibiting unusual RER formations.

An unusual cause of hypercalcemic crisis: Water-clear cell double parathyroid adenoma

Methods: We retrospectively studied 69 surgical RCC cases from August 2014 to February 2016, including 18 cases of clear cell RCC (ccRCC) demonstrating elevated pretreatment serum C-reactive protein (CRP, Group A).

Roles of Loss of Chromosome 14q Allele in the Prognosis of Renal Cell Carcinoma with C-reactive Protein Abnormity