clear cell

clear cell

1. a cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;
2. any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.

clear cell

(klîr)
n.
A cell, especially a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cytoplasm appears clear histologically.
A finely vacuolated, cholesterol-filled cell with central dark nuclei, which is arranged in clusters and located in the midzone or zona fasciculata of the adrenal cortex. Clear cells are the major reservoir for glucocorticoid and sex hormone production when the adrenal gland is stressed

clear cell

(klēr sel)
1. A cell in which the cytoplasm appears empty with the light microscope, as occurs in certain secretory cells of eccrine sweat glands and in the parathyroid glands when the glycogen is unstained;
2. Any cell, particularly a neoplastic one, containing abundant glycogen or other material that is not stained by hematoxylin or eosin, so that the cell cytoplasm is very pale in routinely stained sections.
References in periodicals archive ?
Squamous cell carcinoma in situ arising within clear cell acanthoma.
This differential is further aggravated by the existence of the so-called eosinophilic or oncocytic subtypes of clear cell renal cell carcinoma and chromophobe renal cell carcinoma [4], particularly when secondary regressive tissue alterations such as pseudocystic change and necrosis occur.
She had a past medical history of right RCC, clear cell carcinoma subtype with bilateral adrenal metastasis (T3b, N0, and M1) diagnosed in May 2006.
Clear cell papulosis (CCP) is a benign childhood skin condition.
Sex cord-stromal tumors and clear cell carcinoma can show solid growth patterns with diffuse clear cell morphology which resemble seminoma [7] and differentiating between the disorders can be challenging.
Immunohistostaining showed that hepatocyte nuclear factor-1beta (HNF-1[beta]) was positive, p53 was negative, ER was negative, and progesterone receptor (PgR) was focally positive, indicating that most of the tumor presented the features of clear cell adenocarcinoma (Figure 5).
Mullerian neoplasms of the urinary system are a rare entity of neoplasms that are subdivided into Clear Cell Carcinoma (CCC) and Endometrioid Carcinoma.
The histopathology of the RCC was of a clear cell type (TNM stage pT1 NX G2 L0 V0 R0 M0) and Fuhrmann grade 2 without any sarcomatoid aspect and was treated with a nephrectomy.
Of 51 nephrectomy specimens, 46/51 was RCC; 5/51 were others which include solitary fibrous tumour, clear cell sarcoma, angiomyolipoma and oncocytoma.
Liam Debbage, 31, was diagnosed with clear cell sarcoma 16 months ago after he injured his shoulder playing squash.
Large clear cell adenoma of the parathyroid in a patient with MEN-1 syndrome: ultrastructural study of the tumour exhibiting unusual RER formations.
Methods: We retrospectively studied 69 surgical RCC cases from August 2014 to February 2016, including 18 cases of clear cell RCC (ccRCC) demonstrating elevated pretreatment serum C-reactive protein (CRP, Group A).