clean room

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A highly filtered environment used to manufacture and/or package sterile and high purity products—e.g., microprocessors, pharmaceuticals, and other dust or microbe-sensitive products—to protect personnel, equipment, and products from microbial contamination and to prevent the escape of hazardous substances into the environment
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.

clean room

A controlled environment facility in which all incoming air passes through a filter capable of removing 99.97% of all particles 0.3μ m and larger. The temperature, pressure, and humidity in the room are controlled. Clean rooms are used in research and in controlling infections, esp. for persons who may not have normally functioning immune systems (e.g., individuals who have been treated with immunosuppressive drugs in preparation for organ transplantation).

In very rare instances a child is born without the ability to develop an immune system. Such children are kept in a clean room while waiting for specific therapy such as bone marrow transplantation.

See also: room
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
To give perspective, the ambient outside air in a typical city contains 35 million particles per cubic meter in the size range 0.5 pm and larger in diameter, corresponding to an ISO 9 clean room, while an ISO 1 clean room allows no particles in that size range and only 12 particles per cubic meter of 0.3 pm and smaller.
The university's current clean rooms complex was built in 1987 and underwent significant upgrading in 2003, when the centre was established, and another in 2008.
The company's new Hardwall Cleanroom systems provide one of the best low cost options for growing organization looking to implement a leading class clean room solution.
"Adding the clean rooms allows us to expand our capabilities for our pharmaceutical customers," said Tee Noland, PTI's director of business development.
The filters pull so much air through them, Lebens says, that "if it goes on for years, it can ruin your whole clean room." Luckily, only a few of the new fil- ters were in use and the filter manufacturer corrected the problem readily.
"Above all," says William Bianco, Kinetic Systems' founder and president, "they require meticulous, precise, and contamination-free welds." Such systems are specifically intended for applications such as pumping specialty gases and for duct systems, clean rooms, and everything else that goes into the piping and storing of high-purity gases and liquids.
Many pharmaceutical manufacturers utilize clean rooms during the manufacture and the manipulation of their products.
The company's four other clean rooms are certified Class 10,000 and 100,000 controlled environments with a combined space of 50,000 square feet.
Modular clean rooms are contamination-free environments for product production, research and other sensitive products and processes that require a completely sterile workspace.