clean room


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A highly filtered environment used to manufacture and/or package sterile and high purity products—e.g., microprocessors, pharmaceuticals, and other dust or microbe-sensitive products—to protect personnel, equipment, and products from microbial contamination and to prevent the escape of hazardous substances into the environment

clean room

A controlled environment facility in which all incoming air passes through a filter capable of removing 99.97% of all particles 0.3μ m and larger. The temperature, pressure, and humidity in the room are controlled. Clean rooms are used in research and in controlling infections, esp. for persons who may not have normally functioning immune systems (e.g., individuals who have been treated with immunosuppressive drugs in preparation for organ transplantation).

In very rare instances a child is born without the ability to develop an immune system. Such children are kept in a clean room while waiting for specific therapy such as bone marrow transplantation.

See also: room
References in periodicals archive ?
Food and Drug Administration publishes clean room standards, both required and recommended, for manufacturers of pharmaceuticals and medical devices, so the starting point is to look for doors that are cGMP- and FDA-compliant.
With the rigorous, defined software clean-room method and process specified, the question of whether a legitimate clean room was in place and operating can be addressed by confirming the equivalency of the intent and means employed, verifying the extent to which the defined protocols of separation were practiced, validating the clean-room software-engineering process execution and outcome with respect to convincingly achieving the intended result of a proprietary-free clean system, and reporting the results in terms of findings, rationale, recommendations and consequences.
According to Gary Avalon, chief operating officer, the precision clean room facility satisfies marketplace preferences for goods that have been produced in a clean room environment.
While there are physical limits to how much smaller the items being scrutinised will be and with the Orion microscope "pretty much looking at an atomic scale", further clean room improvements might seem unnecessary.
"The new clean room has already led to us winning another customer, and we intend to attract more this year."
Alcohols will not control fungal spores, but a good quality broad-spectrum biocide may be used weekly/monthly as part of the clean room cleaning protocol to control this.
In the past, relatively few studies were focuses on the flow field created by the interaction between moving objects and approaching air flow and its effect on contaminant control in the clean room technology.
The introduction of the clean room is the latest addition to the range of services available from AxFlow's maintenance facility in Huddersfield.
The ceiling tile, wall paint, and flooring material are not designed for clean room use and thus have a potential for shedding.
1705 Route 46 is a 61,000s/f, fully air-conditioned industrial building with office, flex, lab and clean room space.
Over the past two years, the company has been using "lean manufacturing" and "continuous improvement" to reduce the manufacturing floor space of the facility and to create a "clean room environment." The facility produces laminated paint film products for automotive manufacturers, and a clean room with a low particulate contamination level has been found necessary for the production of paintfilm sheet and lamination of the paintfilm.