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clav·u·lan·ic ac·id(klav'yū-lan'ik as'id),
A β-lactam structurally related to the penicillins that inactivate β-lactamase enzymes in penicillin-resistant organisms; usually used in combination with penicillins to enhance and broaden the spectrum of the penicillins.
A compound, C8H9NO5, originally obtained from the bacterium Streptomyces clavuligerus, that inhibits action of the enzyme beta-lactamase, thus counteracting bacterial resistance to beta-lactam antibiotics. It is used in combination with antibiotics such as amoxicillin to treat infections caused by antibiotic-resistant bacteria.
clavulanic acidA drug that interferes with beta-lactamase enzymes that inactivate many penicillin-type antibiotics, such as AMOXICILLIN. Combined with the antibiotic, this drug can overcome drug resistance.
clav·u·lan·ic ac·id(klav'yū-lan'ik as'id)
A β-lactam structurally related to the penicillins that inactivates β-lactamase enzymes in penicillin-resistant organisms.
clavulanic acid, clavulanate
a beta-lactam product of Streptomyces spp. It binds irreversibly and inhibits β-lactamase produced by many organisms. Used commonly in combination with amoxicillin.