Some recently identified genes that also contribute to AD risk include CLU and PICALM (phosphatidylinositolbinding clathrin
assembly protein), among others.
, cells divide erratically and unevenly a phenomenon that is one of the hallmarks of the disease.
Y828C sequence variation did not colocalize with a clathrin
marker in CHO cells, as opposed to the wild-type, in an experiment using fluorescent probes detected by a confocal laser microscopy (Fig.
Internalization and desensitization of the oxytocin receptor is inhibited by dynamin and clathrin
mutants in human embryonic kidney 293 cells.
is the major protein constituent of the coat that surrounds organelles to mediate selective protein transport.
Schein came to the cagelike molecules because he was curious about clathrin
, a protein that assembles itself in cages.
is involved in moving resources inside and outside cells, and in that process it forms only a handful number of shapes.
Fusion of the ALK gene to the clathrin
heavy chain gene, CLTC, in inflammatory myofibroblastic tumor.
, polysaccharides can be absorbed intact into the blood and lymphatic systems, then delivered to the whole body.
coat is needed for invagination of the cell membrane.
The team determined that this protein is a specialized form of an omnipresent housekeeping protein called clathrin
, which is known to be instrumental in moving proteins between cellular compartments.
Deletion of a putative clathrin
binding domain in the C terminal half by site specific mutagenesis abolished TOR's ability to internalize the adenosine transporter.