Pepper et al., "Inhibition of the classical pathway
of the complement cascade prevents early dendritic and synaptic degeneration in glaucoma," Molecular Neurodegeneration, vol.
Because conventional adenomas can harbor aberrant hypermethylation of CIMP panel markers, (49) CIMP-L CRCs can arise from either the serrated neoplasia pathway or the classical pathway
. At present, methylation assays of CIMP panel markers cannot differentiate between CIMP-L serrated pathway adenocarcinomas and CIMP-L CRCs arising from the classical pathway
Significant difference between different genotypes GG (69.49 [+ or -] 3.17 U/mL) and CG (63.59 [+ or -] 3.65 U/mL) in hemolytic activity in the classical pathway
(p = 0.049) was recorded.
The complement system is a set of enzymes and bioregulators with multiple biological activities, playing a key role in both innate (alternative and lectin pathway) and acquired (classical pathway
It was acknowledged that immune complexes formed by self-antigens and autoantibodies might activate the classical pathway
, generating inflammatory mediators and resulting in tissue damage.
coli produces heme by itself via the classical pathway
. Therefore, the potential AhbD from M.
Loos, "Classical pathway
of activation," in The Complement System, K.T.G.
complement levels divide UV into normocomplementemic (NUV) and hypocomplementem-ic (HUV) forms.
His complement classical pathway
was 325 CH100 U/l (normal 488 - 1 200).
For example, compared with classical pathway
optimization, which focuses on enhancing the biosynthetic pathway of the nutraceutical ingredient, metabolic engineering provides a holistic view of the micro-organism, thereby optimizing the whole production organism.
Complement system can be activated by three different pathways, viz., classical pathway
(CP), alternative pathway (AP), and lectin pathway (LP).
This effect was not achieved by mimicking the classical pathway
of insulin action, but by activating the enzyme AMP-activated protein kinase (AMPK).