class I antigens


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Related to class I antigens: major histocompatibility complex, MHC, HLA complex

class I an·ti·gens

cell-membrane-bound glycoproteins found on most nucleated cells that are coded by human leudocyte antigen genes of the major histocompatibility complex.
Farlex Partner Medical Dictionary © Farlex 2012

class I an·ti·gens

(klas an'ti-jenz)
Cell-membrane-bound glycoproteins that are coded by genes of the major histocompatibility complex.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012
References in periodicals archive ?
Jay used recombinant DNA techniques to insert extra copies of the gene for a class I antigen into malignant (transformed) cells that do not normally show high levels of the surface proteins.
Cryptic Epitopes on Dissociated HLA Class I Antigens. Naturally occurring anti HLA antibodies were detected in nonalloimmunized healthy males [26], and 96 of their target epitopes were defined [16].
It is slightly reactive with the intact HLA class I antigens. Reactivity increased by up to 10-fold with the dissociated antigens (heavy chain only)--when (32m and the peptide are dissociated from the heavy chain (Figure 9).
The HLA class I antigen status in tumor cells may represent a key variable for the efficacy of therapy that relies on CTLs to eliminate the tumor cells [20].
Lack of Surface HLA Class I Antigen and [[beta].sub.m] Expression and Downregulation of Several Antigen-Processing Machinery (APM) Components by the sHCC29 and sHCC63 Cell Lines.