PIGA(redirected from class A GlcNAc-inositol phospholipid assembly protein)
PIGAA gene on chromosome Xp22.1 that encodes a transmembrane protein required for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in GPI-anchor biosynthesis.
Defects in PIGA cause multiple congenital anomalies-hypotonia-seizures syndrome type 2 and paroxysmal nocturnal haemoglobinuria.
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