CLCN1(redirected from clC-1)
CLCN1A gene on chromosome 7q34 that encodes a voltage-gated chloride channel that regulates the electric excitability of skeletal muscle membranes.
CLCN1 mutations cause autosomal recessive generalised myotonia congenita (Becker type) and autosomal dominant myotonia (Thomsen disease).
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.