citrated plasma

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1. the fluid portion of the lymph.
2. the fluid portion of the blood, in which the formed elements (blood cells) are suspended. Plasma is to be distinguished from serum, which is plasma from which the fibrinogen has been separated in the process of clotting. Called also blood plasma. adj., adj plasmat´ic, plas´mic.

Of the total volume of blood, 55 per cent is made up of plasma. It is a clear, straw-colored liquid, 92 per cent water, in which are contained plasma proteins, inorganic salts, nutrients, gases, waste materials from the cells, and various hormones, secretions, and enzymes. These substances are transported to or from the tissues of the body by the plasma.

Plasma obtained from blood donors is given to persons suffering from loss of blood or from shock to help maintain adequate blood pressure. Since plasma can be dried and stored in bottles, it can be transported almost anywhere, ready for immediate use after addition of the appropriate fluid. Plasma can be given to anyone, regardless of blood type. (See also transfusion.)

Plasma volume is sometimes measured in order to calculate the total blood volume. The most common method for determining plasma volume is by injection of a dye (T-1824, called Evans blue) into the circulating blood and, after the dye has been dispersed throughout the body, using the dilution of the dye to calculate the total blood volume.
antihemophilic human plasma normal human plasma that has been processed promptly to preserve the antihemophilic properties of the original blood; used for temporary correction of bleeding tendency in hemophilia.
blood plasma plasma (def. 2).
citrated plasma blood plasma treated with sodium citrate, which prevents clotting.
plasma exchange the removal of plasma from withdrawn blood (plasmapheresis) and retransfusion of the formed elements and type-specific fresh frozen plasma into the donor; done for removal of circulating antibodies or abnormal plasma components.
fresh frozen plasma plasma separated from whole blood and frozen within 8 hours; it contains all the coagulation factors.
plasma thromboplastin antecedent deficiency hemophilia C.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.
References in periodicals archive ?
Citrated plasma spiked in vitro with UH overestimates the degree of aPTT prolongation when compared with ex vivo patients' plasma samples treated with UH.
The current assay methods use citrated plasma and are based on inhibition of bovine thrombin or Xa.
We analyzed FSTL1 concentrations in parallel in serum, citrated plasma, EDTA-treated plasma, and heparin-treated plasma samples obtained from 4 healthy individuals and 6 patients with ACS containing different FSTL1 concentrations (range in serum 7.17-32.07 [micro]g/L).
(4) This test measures the rate of fibrin clot formation after the addition of reptilase to citrated plasma. Reptilase is a snake venom enzyme obtained from Bothrops jararaca or Bothrops atrox.
GDF15 concentrations were determined in citrated plasma samples from 429 apparently healthy elderly individuals included in the population-based SWISCH study (26).
The ISIs for whole blood and citrated plasma with the three monitoring systems were derived according to the conventional WHO orthogonal regression procedure (1, 2).
Samples were from patients who had a D-dimer test (from citrated plasma) ordered as well as available serum obtained during the same blood collection.
Each antibody combination was used to measure the tPA/PAI-1 complex in seven citrated plasma samples containing increased PAI-1 activity [range, 25 000-115 000 IU/L (25-115 IU/mL); mean [+ or -] SD, 68 000 [+ or -] 34 000 IU/L (68 [+ or -] 34 IU/mL)], before and after addition of an excess of active tPA.
The values for S100B from citrated plasma became equivalent to serum values when 5 mmol/L [Ca.sup.2+] was added to the incubation buffer.
Control plasma was obtained by pooling citrated plasma from 10 healthy volunteers.