citrate lyase

cit·rate ly·ase

citrate (pro-3S)-lyase; an enzyme that catalyzes the cleavage of citrate to oxaloacetate and acetate, in the absence of coenzyme A.
References in periodicals archive ?
Garcinia cambogia contains the active ingredient hydroxycitric acid, which is thought to inhibit the body's production of lipids via an enzyme called citrate lyase.
They are supposed to contain 75% hydroxycitric acid, which is said to promote weight loss "because it blocks citrate lyase - the chemical responsible for storing carbohydrates in the body as fat".
HCAP(TM), after permeation through the skin, is digested into HCA by the action of an enzyme inside cells, inhibiting the activity of ATP citrate lyase.
Citrate, converted to Acetyl CoA by ATP citrate lyase (ACL) in the cytoplasm and nucleus, is required for histone acetylation by HATs.
Clinical studies on Citrin exhibit that HCA can help to reduce the appetite, promote satiety, help the burning of fat stored in the body, as well as inhibit new fat formation by the unique citrate lyase inhibition of HCA, which competes with citric acid to bind with the citrate lyase enzyme.
Reactivity and inhibitor potential of hydroxycitrate isomers with citrate synthase, citrate lyase, and ATP citrate lyase.
The accumulated pyruvate enters the gaba shunt pathway and is converted to citrate which is acted upon by citrate lyase and converted to acetyl CoA, used for cholesterol synthesis.
Oxalate was manually measured with Hitachi oxalate oxidase and peroxidase assays (Boehringer Mannheim, Laval, Quebec), and citrate was manually measured with a citrate lyase assay.
Both tissues had very low abundance for ATP citrate lyase.
2 carboxykinase 1 Glyceraldehyde-3-phosphate BTU85042 dehydrogenase ATP citrate lyase BC108138.
The Schiff's bases and their metal complexes of the present invention are useful for the modulation of metal-activated enzymes and metalloenzymes, such as Phenylalanine Hydroxylase, Tyrosine Transaminase, Phenylalanine Transaminase, Tyrosinase, various MMP (Matrix metalloproteases), Superoxide dismutase, 5-Alpha Reductase, and citrate lyase.
Citrate lyase converts citric acid into acetyl-CoA and oxaloacetic acid.