citalopram


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Related to citalopram: Escitalopram

citalopram

 [si-tal´o-pram]
an antidepressant used in the treatment of depressive disorders, administered orally as citalopram hydrobromide.

citalopram

/ci·tal·o·pram/ (si-tal´o-pram)
1. an antidepressant compound used in the treatment of major depressive disorder, administered orally as the hydrobromide.
2. a selective serotonin reuptake inhibitor used as the hydrobromide salt as an antidepressant.

citalopram

(sī-tăl′ō-prăm′)
n.
A drug of the SSRI class, C20H21FN2O, used in its hydrobromide form to treat depression.

citalopram

an antidepressant in the selective serotonin-reuptake inhibitor class.
indication It is used to treat major depressive disorder.
contraindications Known hypersensitivity to this drug prohibits its use. It should not be used with MAO inhibitors. It interacts with several forms of cytochrome P450 and therefore influences many other drugs.
adverse effects Life-threatening effects include convulsions, hemorrhage, first-degree atrioventricular block, and myocardial infarction. Other serious adverse effects include hallucinations, delusions, psychosis, vomiting, asthma, hyperventilation, respiratory infection, dyspnea, bronchitis, pneumonia, angina pectoris, hypertension, palpitations, tachycardia, bradycardia, thrombophlebitis, arthritis, amenorrhea, cystitis, urine retention, and viral infection. Common side effects are numerous, affecting the GI, integumentary, respiratory, cardiovascular, genitourinary, and central nervous systems. Some are also systemic.

citalopram

Celexa® Neurology A serotonin reuptake inhibitor for managing major depression Adverse events Nausea, insomnia, ejaculation disorder, diaphoresis, fatigue Contraindications MAOI therapy
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References in periodicals archive ?
Previously, the citalopram (Celexa) label said some patients might require a dose of 60 mg per day.
Safety warnings issued on citalopram
After 12 weeks of therapy with either citalopram at a flexible dose of 10-60 mg daily or placebo plus the patients' standard antipsychotic agent, citalopram was associated with lower Beck Hopelessness Scale (BHS) scores, and lower likelihood of having suicidal ideation on both the InterSePT Scale for Suicidal Thinking (ISTT) and Hamilton Depression Rating Scale item 3.
SSRI may reduce suicidal ideation in schizophrenia patients: from the annual meeting of the American Association for geriatric psychiatry
Another recent report from the Swedish Medical Birth Registry failed to identify higher rates of congenital malformations associated with prenatal exposure to a number of SSRIs, including fluoxetine, citalopram, paroxetine (Paxil), and sertraline (Zoloft).
Reviewing the safety of SSRIs
Kraus conducted a randomized, double-blind, placebo-controlled study examining the efficacy of citalopram in treating peginterferon-induced depression (Gut 2008;57:531-6).
Treating peginterferon-induced depression
Citalopram (Celexa) is an SSRI approved for depression, but also used for other disorders.
Citalopram reduces hot flashes in randomized phase III trial
A total of 31 of the 38 cases occurred in the early neonatal period in the first week of life, and 18 of these involved neonatal withdrawal symptoms, including jitteriness, rigidity, tremor, and confusion associated with citalopram exposure in the third trimester or throughout pregnancy.
Maternal citalopram tx spurs adverse events
Citalopram belongs to a class of selective serotonin-uptake inhibitor, antidepressant products used in the treatment of depression.
Bentley Pharmaceuticals Receives Approval to Market Branded and Generic Versions of Citalopram in Spain
The results from Targacept's Phase II efficacy trial of mecamylamine as an augmentation therapy to citalopram helped establish the NNR mechanism as a potential new treatment paradigm for depression," said Dr.
Targacept Announces Plans to Develop Enantiomer of Mecamylamine as Augmentation Therapy for Depression
In all, 160 participants were then randomized to citalopram (Celexa) or placebo.
SSRI improves metabolic risk factors, hostility
Both trials involved patients with panic disorder, the first was a European study which compared different doses of citalopram to placebo for 8 weeks of treatment followed by a one year extension phase; the second was a U.
Forest Laboratories Submits Response for Lexapro(R) for Panic Disorder
At a meeting of the same panel in February, one case of an eye malformation (congenital ptosis, eye muscle paresis, and nystagmus) was reported in a baby exposed to the antidepressant citalopram (Celexa) in utero, during the year after citalopram was granted "pediatric exclusivity" by the FDA.
In utero exposure to antidepressants not tied to eye malformations
The data suggest that an add-on treatment of mecamylamine hydrochloride, a broad spectrum nicotinic antagonist, improved symptoms of depression in patients who were inadequate responders to first-line citalopram therapy.
Targacept Presents Data from TRIDMAC(TM) Trial Showing Positive Effects of Mecamylamine as Augmentation Treatment for Depressed Patients

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