citalopram


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Related to citalopram: Escitalopram

citalopram

 [si-tal´o-pram]
an antidepressant used in the treatment of depressive disorders, administered orally as citalopram hydrobromide.

citalopram

/ci·tal·o·pram/ (si-tal´o-pram)
1. an antidepressant compound used in the treatment of major depressive disorder, administered orally as the hydrobromide.

citalopram

(sī-tăl′ō-prăm′)
n.
A drug of the SSRI class, C20H21FN2O, used in its hydrobromide form to treat depression.

citalopram

an antidepressant in the selective serotonin-reuptake inhibitor class.
indication It is used to treat major depressive disorder.
contraindications Known hypersensitivity to this drug prohibits its use. It should not be used with MAO inhibitors. It interacts with several forms of cytochrome P450 and therefore influences many other drugs.
adverse effects Life-threatening effects include convulsions, hemorrhage, first-degree atrioventricular block, and myocardial infarction. Other serious adverse effects include hallucinations, delusions, psychosis, vomiting, asthma, hyperventilation, respiratory infection, dyspnea, bronchitis, pneumonia, angina pectoris, hypertension, palpitations, tachycardia, bradycardia, thrombophlebitis, arthritis, amenorrhea, cystitis, urine retention, and viral infection. Common side effects are numerous, affecting the GI, integumentary, respiratory, cardiovascular, genitourinary, and central nervous systems. Some are also systemic.

citalopram

Celexa® Neurology A serotonin reuptake inhibitor for managing major depression Adverse events Nausea, insomnia, ejaculation disorder, diaphoresis, fatigue Contraindications MAOI therapy
References in periodicals archive ?
Previously, the citalopram (Celexa) label said some patients might require a dose of 60 mg per day.
After 12 weeks of therapy with either citalopram at a flexible dose of 10-60 mg daily or placebo plus the patients' standard antipsychotic agent, citalopram was associated with lower Beck Hopelessness Scale (BHS) scores, and lower likelihood of having suicidal ideation on both the InterSePT Scale for Suicidal Thinking (ISTT) and Hamilton Depression Rating Scale item 3.
Another recent report from the Swedish Medical Birth Registry failed to identify higher rates of congenital malformations associated with prenatal exposure to a number of SSRIs, including fluoxetine, citalopram, paroxetine (Paxil), and sertraline (Zoloft).
Kraus conducted a randomized, double-blind, placebo-controlled study examining the efficacy of citalopram in treating peginterferon-induced depression (Gut 2008;57:531-6).
Citalopram (Celexa) is an SSRI approved for depression, but also used for other disorders.
A total of 31 of the 38 cases occurred in the early neonatal period in the first week of life, and 18 of these involved neonatal withdrawal symptoms, including jitteriness, rigidity, tremor, and confusion associated with citalopram exposure in the third trimester or throughout pregnancy.
Citalopram belongs to a class of selective serotonin-uptake inhibitor, antidepressant products used in the treatment of depression.
The results from Targacept's Phase II efficacy trial of mecamylamine as an augmentation therapy to citalopram helped establish the NNR mechanism as a potential new treatment paradigm for depression," said Dr.
In all, 160 participants were then randomized to citalopram (Celexa) or placebo.
Both trials involved patients with panic disorder, the first was a European study which compared different doses of citalopram to placebo for 8 weeks of treatment followed by a one year extension phase; the second was a U.
At a meeting of the same panel in February, one case of an eye malformation (congenital ptosis, eye muscle paresis, and nystagmus) was reported in a baby exposed to the antidepressant citalopram (Celexa) in utero, during the year after citalopram was granted "pediatric exclusivity" by the FDA.
The data suggest that an add-on treatment of mecamylamine hydrochloride, a broad spectrum nicotinic antagonist, improved symptoms of depression in patients who were inadequate responders to first-line citalopram therapy.