'He may also have been affected by
Cisapride which had been prescribed for stomach and digestive problems.
The Food and Drug Administration has put both the tablet and suspension preparations of
cisapride (Propulsid, Janssen Pharmaceuticals, Titusville, N.J.) on a limited-access program, in the wake of Janssen's decision to stop marketing it in the United States effective July 14.
In one of the larger series, 82% of a cohort of children with pH probe or scintiscan confirmed GER had remission of respiratory symptoms when treated with
cisapride.
-- The labeling for
cisapride has been strengthened with a recommendation to get a 12-lead electrocardiogram in every patient before prescribing the heartburn drug.
Use cautiously with drugs such as
cisapride, erythromycin, or others that prolong the QT interval; moxifloxacin has not been studied with these drugs.
For symptomatic relief of gastroesophageal reflux disease,
cisapride was no better than placebo in a three-way comparison of
cisapride, omeprazole, and placebo.
Propulsid (
cisapride) may be useful, but an electrocardiogram must be done prior to use.
The panel recommended that Bayer conduct several postmarketing studies of moxifloxacin, including a prospective study on the risk of QT prolongation and an interaction study with
cisapride, which is widely used and known to extend the QT interval.
His constipation issues are treated with over-the-counter Miralax and prescription
cisapride.
The other medications such as neostigmine, pyridostigmine,
cisapride, trimebutine maleate, metoclopramide, dom-peridone, and laxatives were given according to the standard pediatric doses.
Your veterinarian may also suggest a prescription medication such as metoclopramide, or off label use of a drug called
cisapride, to enhance gastric and intestinal motility.