circumsporozoite protein


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circumsporozoite protein

one of two proteins (the other is thrombospondin-related adhesive protein) involved in sporozoite recognition of host cells in malaria.

cir·cum·spor·o·zo·ite pro·tein

(sĭr'kŭm-spōr-ō-zō'īt prō'tēn)
One of two proteins (the other is thrombospondin-related adhesive protein) involved in sporozoite recognition of host cells in malaria.
References in periodicals archive ?
AMA: Apical membrane antigen APL: Anopheles plasmodium-responsive leucine-rich repeat protein CSA: Circumsporozoite protein EBA: Erythrocyte-binding antigen EBL: Erythrocyte-binding ligand ECs: Endothelial cells EEF: Exoerythrocyte form Imd: Immune deficiency iRBCs: Infected red blood cells JNK: Janus kinase KC: Kupffer cells LRIM1: Leucine-rich repeat protein 1 MHC: Major histocompatibility complex MSPs: Merozoite surface proteins RBL: Reticulocyte binding-like REL: Relish ROS: Reactive oxygen species STAT: Signal transducers and activators of transcription TEP: Thioester-containing protein TLR: Toll-like receptors.
Frevert, "Malaria circumsporozoite protein inhibits the respiratory burst in Kupffer cells," Cellular Microbiology, vol.
Naturally acquired CD8+ cytotoxic T lymphocytes against the Plasmodium falciparum circumsporozoite protein. J Immunol.
circumsporozoite protein rates between the three villages ([chi square] = 0.7, df = 2, and P = 0.68).
The circumsporozoite protein (CSP) has been recognised as a potential target in the development of vaccines focused on the earlier stages of malaria infection.
vivax circumsporozoite protein (CSP), which covers the parasite surface during the initial stages of infection.
A preliminary evaluation of a recombinant circumsporozoite protein vaccine against Plasmodium falciparum malaria.
Recognition of dominant T cell-stimulating epitopes from the circumsporozoite protein of Plasmodium falciparum and relationship to malaria morbidity in Gambian children.
Of approximately 870 anopheline mosquitoes tested, five pools (four to six mosquitoes per pool) captured within 2-6 miles of the patients' homes tested positive for P vivax-210 circumsporozoite protein by using a field test (VecTest[TM] [Medical Analysis Systems, Inc., Camarillo, California]) on September 25 and 27 and October 1, 6, and 11.
The circumsporozoite protein covers the sporozoite--the nascent stage of Plasmodium falciparum, which is the protozoan that causes malaria.
The circumsporozoite protein (csp) gene, which is known to be critical for plasmodia sporozoite motility and hepatocyte invasion (23), has been shown to be variable in length and is a sequence of the tandemly repeated peptide units in P.
Garboczi et al., "Direct measurement of the interactions of glycosaminoglycans and a heparin decasaccharide with the malaria circumsporozoite protein," Biochemistry, vol.