ciprofloxacin


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Related to ciprofloxacin: metronidazole

ciprofloxacin

 [sip″ro-flok´sah-sin]
a quinolone antibacterial agent effective against many gram-positive and gram-negative bacteria, including some strains resistant to other agents such as penicillins.

ciprofloxacin

/cip·ro·flox·a·cin/ (sip″ro-flok´sah-sin) a synthetic antibacterial effective against many gram-positive and gram-negative bacteria; used as the hydrochloride salt.

ciprofloxacin

(sĭp′rō-flŏk′sə-sĭn)
n.
A semisynthetic analog of fluoroquinolone that is administered orally and has a broad spectrum of antibiotic activity.

ciprofloxacin

Cipro® Antibiotics A broad-spectrum–GNRs, staphylococci, fluoroquinolone with limited activity against streptococci, anaerobes Indications Acute sinusitis, acute exacerbation of chronic bronchitis, UTI, acute cystitis in ♀, bacterial prostatitis, intra-abdominal infection, skin, bone and joint infection, infectious diarrhea, typhoid fever, gonorrhea Adverse effects GI pain, N&V, diarrhea, seizures, rash, photosensitivity. See Fluoroquinolone.

ciprofloxacin

A fluoroquinolone antibiotic used to treat urinary infections and, as eye drops, for the treatment of corneal ulcers. The drug acts by binding to the enzyme gyrase. Mutations lead to an alteration in the structure of this enzyme leading to antibiotic resistance. Current research suggests the possibility of preventing this process. The drug is on the WHO official list. Brand names are Ciproxin and Ciloxan.

ciprofloxacin

; Ciproxin quinolone antibacterial agent active against Gram-positive and Gram-negative bacteria, Pseudomonas and some mycobacteria

antibiotic 

1. Pertaining to the ability to destroy or inhibit other living organisms.
2. A substance derived from a mould or bacterium, or produced synthetically, that destroys (bactericidal) or inhibits the growth (bacteriostatic) of other microorganisms and is thus used to treat infections. Some substances have a narrow spectrum of activity whereas others act against a wide range of both gram-positive and gram-negative organisms (broad-spectrum antibiotics). Antibiotics can be classified into several groups according to their mode of action on or within bacteria: (1) Drugs inhibiting bacterial cell wall synthesis, such as bacitracin, vancomycin and the β-lactams based agents (e.g. penicillin, cephalosporins (e.g. ceftazidime, ceftriaxone, cefuroxime). (2) Drugs affecting the bacterial cytoplasmic membrane, such as polymyxin B sulfate and gramicidin. (3) Drugs inhibiting bacterial protein synthesis, such as aminoglycosides (e.g. amikacin sulfate, framycetin sulfate, gentamicin, neomycin sulfate and tobramycin), tetracyclines, macrolides (e.g. erythromycin and azithromycin) and chloramphenicol. (4) Drugs inhibiting the intermediate metabolism of bacteria, such as sulfonamides (e.g. sulfacetamide sodium) and trimethoprim. (5) Drugs inhibiting bacterial DNA synthesis, such as nalixidic acid and fluoroquinolones (e.g. ciprofloxacin, levofloxacin, moxifloxacin, norfloxacin and ofloxacin). (6) Other antibiotics such as fusidic acid, the diamidines, such as propamidine isethionate and dibrompropamidine. Syn. antibacterial. See antiinflammatory drug; fusidic acid.

ciprofloxacin,

n brand name: Cipro;
drug class: fluoroquinolone antiinfective;
action: a broad-spectrum bactericidal agent that inhibits enzyme deoxyribonucleic acid (DNA) gyrase needed for replication of DNA;
uses: adult urinary tract infection, uncomplicated gonorrhea, typhoid fever; effective against some periodontal organisms.

ciprofloxacin

a fluoroquinolone antibiotic with particularly good activity against gram-negative bacteria, including Enterobacteriaceae and Pseudomonas aeruginosa. It is used mainly in urinary tract infections.
References in periodicals archive ?
For example, that analysis did not take into consideration the theoretical decrease in ceftriaxone-resistant infections expected with use of ciprofloxacin as an alternative regimen, nor did it take into account other potential benefits of oral therapy over injection therapy.
Keywords: Chronic Suppurative Otitis Media (CSOM), Topical Ciprofloxacin, Topical Neomycin.
Radiochemical purity of the 99mTc- ciprofloxacin was analyzed by ITLC, PC and RP- HPLC.
Ciprofloxacin orally + Ciprofloxacin parenterally + Parenteral fluid with Sodium bicarbonate + Rice bran mixed with broken barley grains (Group V)
These factors have contributed to increased ciprofloxacin resistance in Salmonella enterica serovars Typhi and Paratyphi A (10).
A correlation between resistance to nalidixic acid and reduced susceptibility to ciprofloxacin and other Flouroquinolones have been reported by several authors.
The three patients who died received ciprofloxacin due to prior antibiotic treatment failure.
Ciprofloxacin may be successfully used as a second choice drug after chloramphenicol, the gold standard for typhoid fever.
The present study therefore was design to estimate the disposition kinetics of ciprofloxacin a commonly used antibiotic in normal and alloxan induced diabetic rabbits.
Thus far, there have not been any clear documents based on investigation of the iron-lowering effect of ciprofloxacin in tissues such as the liver or heart.
The majority of children at the day care center received rifampin, and staff members received ciprofloxacin for antibiotic prophylaxis.