cinoxacin


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cinoxacin

 [sin-ok´sah-sin]
a quinolone antimicrobial agent administered orally in the treatment of urinary tract infections due to Escherichia coli, Proteus mirabilis, P. vulgaris, Klebsiella species, including K. pneumoniae, and Enterobacter species.

cinoxacin

A quinolone antibiotic drug used mainly to treat urinary infections. A trade name is Cinobac.
References in periodicals archive ?
Table 1 shows that the elution order of nalidixic acid and cinoxacin was reversed as the volume of acidic additive in the mobile phase was increased to 4 ml or higher.
Antibiotics discs used in the experiment included Ticarcillin (70ug), Cefixime (5ug), Cloxacillin (1ug), Sulphaphenazol (200ug), Gentamicine (10ug), Amoxicillin (30ug),Vancomycin (30ug), Ceftaxime (30ug), Ceftazidine (30ug), Amoxicillin (25ug), Cefuroxime (30ug), Ciprofloxacillin (5ug), Ampicillin (10ug), Oxacillin (1ug), Amicacin (30ug), Azlocillin (75ug), Piperacillin Tazabactam (100:10 ug), Ticarcillin Calvanic acid (75:10ug), Triple Sulphas (300ug), Cinoxacin (100ug), Mupiracin (5ug), Spectinomycin (100ug), Chloramphenicol (25ug), Trimethoprim (30ug).
In the present findings, 55.6% of the isolates from buffalo and 71.4% from cattle were found sensitive to cinoxacin. Gupta et al.
Quiros, "Ni(II) and Zn(II) complexes with cinoxacin. Synthesis and characterization of M[(Cx).sub.2][(DMSO).sub.n] [([H.sub.2]O.sub.)m] (n = 0, 2; m =2, 4).
This is supported by the study of Turner et al28 who reported that single amino acid substitutions in GyrA was sufficient for resistance to the quinolones nalidixic acid and cinoxacin, but resistance to the fluoroquinolones (gatifloxacin, ofloxacin, ciprofloxacin, enrofloxacin and moxifloxacin) required two substitutions in GyrA and one in ParC.
Cross-resistance among cinoxacin, ciprofloxacin, DJ-6783, enoxacin, nalidixic acid, norfloxacin, and oxolinic acid after in vitro selection of resistant populations.
(2005) reported that cinoxacin (antibiotic) had remarkable effect on the cellular and sub- cellular structure of Chlorella sp., including pronounced anti-chloroplastal and microbial effect even at far lower concentration then used in the current studies.
Urinary germicides include cinoxacin (Cinobac) [C], methenamine [C], nalidixic acid (NegGram) [C], and nitrofurantoin (Macrodantin) [B].
Separation of levofloxacin, ciprofloxacin, gatifloxacin, moxifloxacin, trovafloxacin and cinoxacin by high performance liquid chromatography: application to levofloxacin determination in human plasma.
The reporting of antimicrobials that achieved clinically adequate concentrations only in the urine (cinoxacin, nitrofurantoin, norfloxacin, trimethoprim, etc) was considered unacceptable performance for these 3 samples.
Fiscal year sales and earnings were also boosted by sales of other new products approved during the 1992 calender year, including cinoxacin, baclofen, minocycline and metaproterenol syrup.
Cinoxacin (Cinobac) is rated category B, but there are no fetal risk or breast-feeding data on this drug.