This article which consisted of findings of a recent large clinical case series reported in medical literature is constituted for the purpose of screening the four types of the ablative surgical treatment methods (i.e., anterior cingulotomy
, anterior capsulotomy, subcaudate tractotomy, limbic leucotomy) and their safety and efficacy in patients with TRMD.
Barcia et al (2007) and Leiphart & Valone-III (2010) recognized that the most frequent psychosurgeries are anterior capsulotomy, which have been shown beneficial for general anxiety and obsessive-compulsive disorders, and anterior cingulotomy
, which have shown improvements for depression, bipolar and schizoaffective disorders.
Surgeries such as anterior cingulotomy
, anterior capsulotomy, subcaudate tractotomy, and limbic leucotomy have been shown to effectively reduce depressive symptoms.
Of note, the anterior cingulate also is the target for cingulotomy
, an established surgical treatment for OCD.
Later on, various neuroscientists around the world started patenting newer and safer modern psychosurgical procedures, such as: anterior cingulotomy
(37), subcaudate tractotomy (38), limbic leukotomy (39), anterior capsulotomy (40) and, more recently, deep brain stimulation.
DREZ lesioning, myelotomy, tractotomy, cingulotomy
, or thalamotomy, in the hope of removing the short-circuited, dysfunctional pain-generating nerves from the normal neural system, or interrupting the feedback pathway to the brain.
He was known to have been abusing opium for 5 years and was offered cingulotomy
for his drug abuse problem.
Despite that, subcaudate tractotomy, dorsal anterior cingulotomy
, anterior capsulotomy and limbic leukotomywere were still limitedly applied due to the complications such as obesity, cognitive impairment, personality changes and epilepsy.
Stereotactic radiofrequency thermal cingulotomy
for obsessive-compulsive disorder.
A procedure called stereotactic anterior cingulotomy
(SAC) was associated with significantly reduced obsessional symptoms in 48 percent of study subjects, according to a paper presented in 2012 at a meeting of the American Association of Neurological Surgeons.
The study enrolled six participants who were scheduled to undergo cingulotomy
- a procedure in which a small, precisely placed lesion is created within the ACC - to treat severe obsessive compulsive disorder (OCD) that has not responded to other types of treatment.