cingulin

A rod-shaped homodimeric (108 kD subunits) protein on the cytoplasmic domain of vertebrae tight junctions encoded by CGN on chromosome 1q21. Cingulin is a marker of epithelial differentiation and plays a role in cell proliferation, and in inhibiting Rho signaling.

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Even more, they demonstrated markers such as tight junction including ZO-1, E-cadherin, and cingulin, which indicated that a protective ultrastructure barrier has formed and could probably protect the engineered bladder tissues from urine [15, 32].

Urine-Derived Stem Cells: The Present and the Future

The tight junction scaffolding protein cingulin regulates neural crest cell migration.

Transicion epitelio-mesenquima y migracion celular en celulas de la cresta neural y celulas metastasicas de carcinomas. Revision de la literatura

Likely, VEGF administration to human brain endothelial cells increases permeability of the monolayer and downregulates claudin-5 and occludin, but not junctional adhesion molecule-1 (JAM-1), cingulin, peripheral plasma membrane protein (CASK), or ZO-1 [92].

Blood-Brain Barrier Disruption Induced by Chronic Sleep Loss: Low-Grade Inflammation May Be the Link

Transmembrane proteins (such as occludin, tricellulin, claudins, and junctional adhesion molecule) interact with cytoplasmic peripheral membrane proteins (such as ZO-1, ZO-2, ZO-3, and cingulin) that constitute the frames of tight junctions [32].

Protective effect of Huoxiang Zhengqi oral liquid on intestinal mucosal mechanical barrier of rats with postinfectious irritable bowel syndrome induced by acetic acid

The TJ-associated membrane proteins comprise occludin, tricellulin (also called marvelD2), cingulin, claudins (CL-1, CL-3, CL-5), junction-associated molecules of the immunoglobulin superfamily (JAMs), zona occludens proteins (ZO-1, ZO-2, ZO-3), 7H6, and AF-6 [7, 31, 32].

Neurovascular unit in chronic pain

TJ proteins identified include transmembrane proteins; occludin and claudin, and cytoplasmic plaque proteins; ZO-1, ZO-2, ZO-3, cingulin, and 7H6.

Characterizations of rasa chenduram (Mercury based) and naga parpam (zinc based) preparations: physicochemical and in vitro blood compatibility studies

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