cingulin

A rod-shaped homodimeric (108 kD subunits) protein on the cytoplasmic domain of vertebrae tight junctions encoded by CGN on chromosome 1q21. Cingulin is a marker of epithelial differentiation and plays a role in cell proliferation, and in inhibiting Rho signaling.

References in periodicals archive ?

The tight junction scaffolding protein cingulin regulates neural crest cell migration.

Transicion epitelio-mesenquima y migracion celular en celulas de la cresta neural y celulas metastasicas de carcinomas. Revision de la literatura

Likely, VEGF administration to human brain endothelial cells increases permeability of the monolayer and downregulates claudin-5 and occludin, but not junctional adhesion molecule-1 (JAM-1), cingulin, peripheral plasma membrane protein (CASK), or ZO-1 [92].

Blood-Brain Barrier Disruption Induced by Chronic Sleep Loss: Low-Grade Inflammation May Be the Link

TJ proteins identified include transmembrane proteins; occludin and claudin, and cytoplasmic plaque proteins; ZO-1, ZO-2, ZO-3, cingulin, and 7H6.

Characterizations of rasa chenduram (Mercury based) and naga parpam (zinc based) preparations: physicochemical and in vitro blood compatibility studies

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