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Before the discovery of cinchona bark, malaria had no known relief, even though the disease had ravaged the western world for millennia.
Instead, the bark was used to prepare a decoction of all the cinchona alkaloids, known as `totaquinine' (in addition to quinine, cinchona bark contains the anti-malarial alkaloids quinidine, cinchonine and cinchonidine).
In 1654, the future Charles II of England also caught malaria and was successfully treated with cinchona bark by his own doctor Robert Talbor, and these successes definitively endorsed the product.
Sydenham's therapy consisted of a carefully regulated diet, fresh air in the sick room, abundant liquids, cooling drinks for fever, iron for anemia, mercurial inunctions for syphilis until the patient salivates freely, cooling air for smallpox, horseback riding for patients with tuberculosis to provide fresh air and exercise, his own laudman preparation for heart ailments, powdered deer horn (a form of line) fo dysentry, and cinchona bark for malaria.
Quinine comes from cinchona bark and is used to fight malaria.
Cure's Rum ($10) mixes rum with Lillet Blanc that's infused with oranges and cinchona bark, preserved-rhubarb liqueur, and sumac bitters; a dehydrated orange wheel set on the rim of the glass is topped with a rich Campari syrup and a mountain of sumac foam.