cicatricial alopecia


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alopecia

 [al″o-pe´shah]
loss of hair; baldness. The cause of simple baldness is not yet fully understood, although it is known that the tendency to become bald is limited almost entirely to males, runs in certain families, and is more common in certain racial groups than in others. Baldness is often associated with aging, but it can occur in younger men. minoxidil has been approved as a topical treatment for male pattern baldness. Approximately one-third of the men undergoing this therapy have experienced hair regrowth. The effects of the drug take several months to develop and new hair growth may be limited; the hair is lost if treatment is discontinued. Hair transplants are also available to selected patients. Many men opt for no treatment.

Alopecia as an outcome of chemotherapy for a malignancy can be very distressing. The loss of hair usually is temporary and the hair will grow back after the course of treatment is completed. Male patients may feel more comfortable wearing a hat or cap when out in public. Female patients who wish to wear a wig are encouraged to obtain one that is lightweight and the same color as their hair. Having a hairdresser cut the wig to the patient's usual hair style can increase self-esteem. A kerchief or head scarf can be worn around the house if it is more comfortable than a wig. Receipts for wigs, hairpieces, and other headcovering should be saved; they are tax-deductible medical expenses when related to chemotherapy.
androgenetic alopecia (alopecia androgene´tica) a progressive, diffuse, symmetric loss of scalp hair. In men it begins in the twenties or early thirties with hair loss from the crown and the frontal and temple regions, ultimately leaving only a sparse peripheral rim of scalp hair (male pattern alopecia or male pattern baldness). In females it begins later, with less severe hair loss in the front area of the scalp. In affected areas, the follicles produce finer and lighter terminal hairs until terminal hair production ceases, with lengthening of the anagen phase and shortening of the telogen phase of hair growth. The cause is unknown but is believed to be a combination of genetic factors and increased response of hair follicles to androgens.
alopecia area´ta hair loss in sharply defined areas, usually the scalp or beard.
alopecia ca´pitis tota´lis loss of all the hair from the scalp.
cicatricial alopecia (alopecia cicatrisa´ta) irreversible loss of hair associated with scarring, usually on the scalp.
congenital alopecia (alopecia congenita´lis) congenital absence of the scalp hair, which may occur alone or be part of a more widespread disorder.
alopecia limina´ris hair loss at the hairline along the front and back edges of the scalp.
male pattern alopecia see androgenetic a.
moth-eaten alopecia syphilitic alopecia involving the scalp and beard and occurring in small, irregular scattered patches, resulting in a moth-eaten appearance.
symptomatic alopecia (alopecia symptoma´tica) loss of hair due to systemic or psychogenic causes, such as general ill health, infections of the scalp or skin, nervousness, or a specific disease such as typhoid fever, or to stress. The hair may fall out in patches, or there may be diffuse loss of hair instead of complete baldness in one area.
alopecia tota´lis loss of hair from the entire scalp.
alopecia universa´lis loss of hair from the entire body.

scar·ring al·o·pe·ci·a

alopecia in which hair follicles are irreversibly destroyed by scarring processes including trauma, burns, lupus erythematosus, lichen planopilaris, scleroderma, folliculitis decalvans, or of uncertain cause (pseudopelade).

scar·ring al·o·pe·ci·a

(skahr'ing al'ō-pē'shē-ă)
Skin condition in which hair follicles are irreversibly destroyed by scarring processes including trauma, burns, lupus erythematosus, lichen planopilaris, scleroderma, folliculitis decalvans, or of uncertain cause (pseudopelade).
Synonym(s): cicatricial alopecia.
References in periodicals archive ?
Central centrifugal cicatricial alopecia. Indian Dermatol Online J 2012; 3: 50-1
Cotsarelis et al., "Summary of North American Hair Research Society (NAHRS)--Sponsored workshop on cicatricial alopecia, Duke University Medical Center, February 10 and 11, 2001," Journal of the American Academy of Dermatology, vol.
Primary cicatricial alopecia: histopathologic findings do not distinguish clinical variants.
Scalp showed subtotal cicatricial alopecia. Toe nails were dystrophic and malformed, especially of great toe.
In three-fourths of cases, doctors would never have known their patients had such obvious conditions as severe cicatricial alopecia, since women wore elaborate braids, weaves, wigs, and hair attachments to disguise the often disfiguring conditions.
Moreover, scalp biopsy is an invasive method required for the diagnosis of cicatricial alopecia. Dermoscopy is a new and valuable tool in the diagnosis of alopecias.2,3 It has become an integral part of diagnosing scalp disorders and differentiating cicatricial from noncicatricial alopecia.
INTRODUCTION: Tufted folliculitis is a rare entity of the scalp that resolves with cicatricial alopecia within multiple hair tufts emerging from dilated follicular orifices (1).
Jenna O'Neill, a dermatologist who practices in Winston-Salem, N.C., was given the award for her work in characterizing the genetic basis of central centrifugal cicatricial alopecia.
The following scarring and nonscarring alopecias should be considered in the differential diagnosis: dissecting cellulitis of the scalp, central centrifugal cicatricial alopecia (CCCA), acne keloidalis nuchae, erosive pustular dermatosis, lichen planopilaris (LPP), inflammatory tinea capitis, and secondary syphilis.
a: With central centrifugal cicatricial alopecia (CCC alopecia), the hair loss begins at the top of the scalp and progressively covers a larger area, commonly resulting in scalp itching and tenderness.
Her presentation reviewed treatment for key conditions including seborrheic dermatitis, alopecia, central centrifugal cicatricial alopecia, hair transplants and acne keloidalis, as well as advances in laser hair removal for pseudofolliculitis barbae.