chymase


Also found in: Dictionary, Thesaurus, Encyclopedia, Wikipedia.

chy·mo·sin

(kī'mō-sin),
An aspartic proteinase structurally homologous with pepsin, formed from prochymosin; the milk-curdling enzyme obtained from the glandular layer of the stomach of the calf. Acts on a single peptide bond (-Phe-Met-) in κ-casein.
Synonym(s): chymase, pexin, rennase, rennet, rennin

chymase

[kī′mās]
a serine protease present in human mast cells, most prominent in skin and connective tissue, where it can cleave angiotensin and stimulate mucous glands.

chymase

(kī′mās)
An enzyme in gastric juice that accelerates the action of the pancreatic enzymes.

chymase

see RENNIN.
References in periodicals archive ?
If this becomes known, he observes, "then a whole host of pharmacological agents that act on cells that produce chymase will become useful in treating EB.
Tryptase and chymase enzyme activity in the MCG preparation was measured as described previously (17).
Tryptase and chymase are the predominant proteases present in MCGs.
Mast cell chymase and tryptase in abdominal aortic aneurysm formation.
Chymase mediates mast cell-induced angiogenesis in hamster sponge granulomas.
Selective conversion of big endothelins to tracheal smooth muscle-constricting 31-amino acid-length endothelins by chymase from human mast cells.
Dipeptidyl peptidase I is essential for activation of mast cell chymases, but not tryptases, in mice.