chylomicrons


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chylomicrons

Microscopic globules, 80 to 1000 nanometres in diameter, of fat, phospholipids, cholesterol, fat-soluble vitamins and other materials. Chylomicrons are formed by the epithelium of the small intestine and are found in the blood during the ingestion of dietary fats, etc. The size of chylomicrons relates to the proportion of fats in the diet, being greatest after high-fat meals. Chylomicrons, and some of their contents are broken don in the liver and the constituents released.
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Individual triglyceride-rich lipoproteins, chylomicron remnants, intermediate density lipoproteins (IDL), very low density lipoproteins (VLDL), or particles of differing size and composition may be more closely related to CHD.
Triglyceride, high density lipoprotein, and coronary heart disease
Exogeneous pathway: after the intestinal absorption and assembly on apo B48 of dietary fatty acids and sterols, chylomicrons transport lipids to tissues and finally the liver.
Laboratory investigations in lipidology
Given that chylomicrons are not found in body fluid specimens from nonchyle sources, the presence of chylomicrons in a body fluid is used to identify a chylous effusion.
A Man with Recurrent Ascites after Laparoscopic Cholecystectomy
Bengtsson-Olivecrona, "Lipoprotein lipase enhances the binding of chylomicrons to low density lipoprotein receptor-related protein," Proceedings of the National Academy of Sciences of the United States of America, vol.
The LDL Receptor-Related Protein 1: At the Crossroads of Lipoprotein Metabolism and Insulin Signaling
The turbidity seen in lipemia is mainly due to the presence of chylomicrons. These large particles create light scatter, resulting in elevated absorbance levels that impact colorimetric determinations.
Lipemia and the CBC, immunohematology results
[sup][2] TG level between 500 and 1000 mg/dl accompanied by lactescent serum (chylomicrons are formed at TG levels >500 mg/dl, which makes the serum milky in color) should raise a high degree of suspicion, especially if no other obvious etiology of AP is apparent or when estimation of TG has been delayed.
Clinical Study of 224 Patients with Hypertriglyceridemia Pancreatitis
TRLs (very low-density lipoprotein (VLDL) and chylomicrons (CM)) reduce cholesterol content of high-density lipoproteins (HDL) and decrease the size of low-density lipoproteins (LDL) which increase the propensity for vascular endothelial infiltration and oxidation [8].
Exercise and dietary-mediated reductions in postprandial lipemia
The sieve's place in the treatment of septic shock syndrome (due to TNF alpha and other inflammatory cytokines) from endotoxin activation of the reticulo-endothelial system, especially the liver macrophages (Kuppfer cells) being negated by infusion of chylomicrons (21).
T.H. Pullar memorial address. Pathology: the study of structure and function in health and diseases
PON1 is present in HDL but also in lipoprotein-deficient serum, in VLDL and in chylomicrons. PON1 protects lipids in lipoproteins, in macrophages and in erythrocytes from oxidation.
Paraoxonases and cardiovascular diseases: pharmacological and nutritional influences
(5) The primary function of LPL is the hydrolysis of triglycerides of very-low-density lipoproteins (VLDLs) and chylomicrons (CM), thereby delivering free fatty acids to muscle and adipose tissue for energy production or storage.
Severe hypertriglyceridaemia as a result of familial chylomicronaemia: the Cape Town experience
The fluid in the thoracic duct assumes this milk-like, or emulsion, appearance because it is a mixture of lymph, and triglyceride fat (chylomicrons).
Pleural effusion--a review
Objective: This study aimed to investigate effects of chronic black tea consumption on concentrations of chylomicrons and chylomicron remnants using plasma concentrations of apolipoprotein B-48 as a marker.
Effect of black tea on the fasting concentrations of chylomicrons and chylomicron remnants in humans. (Original Research)

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