chylomicronemia

chylomicronemia

 [ki″lo-mi″kro-ne´me-ah]
an excess of chylomicrons in the blood.

chy·lo·mi·cro·ne·mi·a

(kī'lō-mī'krō-nē'mē-ă),
The presence of chylomicrons, especially increased numbers in the circulating blood, as in type I familial hyperlipoproteinemia.
See also: familial chylomicronemia syndrome.

chy·lo·mi·cro·ne·mi·a

(kī'lō-mī-krō-nē'mē-ă)
The presence of chylomicrons, especially an increased number, in the circulating blood, as in type I familial hyperlipoproteinemia.
Synonym(s): chylomicronaemia.
References in periodicals archive ?
Improving glycemic control in diabetic patients showing fasting chylomicronemia will usually obviate the need for pharmacologic intervention.
Akcea Therapeutics (AKCA), an affiliate of Ionis Pharmaceuticals (IONS), announced that the final study results from the Phase 3 APPROACH study evaluating Waylivra in patients with familial chylomicronemia syndrome were published in the August 8 issue of The New England Journal of Medicine, or NEJM.
- The US Food and Drug Administration has granted orphan drug designation to ARO-APOC3 for the treatment of familial chylomicronemia syndrome, US-based Arrowhead Pharmaceuticals, Inc.
Therapeutic plasma exchange in patients with chylomicronemia syndrome complicated by acute pancreatitis.
Waylivra is under regulatory review in the U.S., Europe and Canada for the treatment of people with familial chylomicronemia syndrome (FCS).
Familial chylomicronemia syndrome (FCS) is a rare inherited lipid disorder that poses significant clinical and psychosocial burdens on patients.
The Metabolism and Endocrinology Products Advisory Committee, a division of The US Food and Drug Administration (FDA), has voted 12-8 to support approval of United States-based Akcea Therapeutics' Waylivratm (volanesorsen) intended for the treatment of familial chylomicronemia syndrome (FCS), it was reported on Friday.
a Study of Volanesorsen (formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome (APPROACH) and the Cardiovascular Outcomes for People Using Anticoagulation Strategies (COMPASS) trial, [13] have shown a serum TG reduction of up to 50% with the use of volanesorsen, an apo C3 inhibitor, when used as monotherapy in the management of dyslipidaemia.
Although patients with a non-HDL cholesterol greater than 3.75 mmol/L require a fasting lipid profile including a triglyceride level, screening for non-fasting triglyceride can be informative since it may predict cardiovascular disease [26] and can detect chylomicronemia leading to pancreatitis prevention [27].
My first independent scientific project was to understand why patients with lipoprotein lipase (LPL) deficiency, the chylomicronemia syndrome, and severely increased plasma triglycerides did not develop cardiovascular disease.
Schwandt, "Treatment of primary chylomicronemia due to familial hypertriglyceridemia by w-3 fatty acids," Metabolism, vol.
An absence of GPIHBP1 abolishes the entry of LPL into capillaries, causing severe chylomicronemia and an accumulation of catalytically active LPL in the interstitial spaces (Voss et al., 2011).