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The activity of laughing; the manifestation of mirth or joy, or, less commonly, sarcasm or scorn
Alternative medicine See Laughter club, Laughter therapy, Laughter yoga
Neurology Spasmodic and largely involuntary expirations often accompanied by inarticulate vocalisations, generally evoked by mirth
Physiology Laughter increases blood flow to the brain and activates neural networks—e.g., nucleus accumbens (NAcc) and amygdala. Functional MRI data suggests that the increase in blood flow to NAcc evoked by extreme humour is similar to that triggered by monetary gain or use of some addictive drugs; a key symptom of depression is the lack of a sense of reward from previously rewarding activities—e.g., humour
Psychiatry Laughter is regarded as the most effective coping skill for anxiety-panic disorders and may temporarily alleviate the symptoms of anxiety and depression


A series of inarticulate sounds produced as an expression of emotion, usually happiness or mirth. The role of humor and laughter in promoting a positive attitude and health and in preventing the progress of some diseases has been documented esp. when it is combined with proven medical therapies.

compulsive laughter

Laughter without cause, occurring in certain psychoses, esp. schizophrenia.

pathological laughter

Uncontrolled laughter (occasionally accompanied by, or alternating with, uncontrolled crying), caused by pseudobulbar lesions of the brain. These lesions may result from lacunar strokes, multiple sclerosis, anoxic brain injury, and other forms of brain injury.
References in periodicals archive ?
Based in Leicestershire, Chuckle Monster provides a fast, simple personalised greeting card service for all occasions.
Eason's calling repertory included a short hail call built on the four-to-six-note hen mallard's call, with a potpourri of clucks and chuckles when the birds were overhead.
We are chatting at Molineux Stadium where the brothers are launching this year's Wolverhampton The Chuckle Brothers get a taste for |management in the dugout at Wolves Grand Theatre panto, Peter Pan.
While this candidacy will hold no weight in any of the primaries, caucuses, or conventions, the Giggle Chuckle Party is an innovative way to laugh amid all of the phone calls, advertisements, and rallies between now and November.
Will he win and stop the Chuckle Brothers in their attempt to spoil his evil and wicked plan?
Join Paul and Barry Chuckle as they arrive accidentally at Pigsnorts School of Magic where the evil Lord Fonterall is plotting to take over the school.
ENTHUSIASTIC comedy duo the Chuckle Brothers bring their tour to South Wales next week, writes Wil Treasure.
I COULDN'T help but chuckle when I read how Bertie is in no rush back to the Dail since he quit as Taoiseach.
Most of these encounters are pathetic at best and a few will make you chuckle.
Cold Ones is always a good chuckle, and this issue has a drunken road trip to Oregon (aren't they all?
Characters from his pen describe the Big Bang using hand gestures and chuckle over a good algebraic equation.