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The activity of laughing; the manifestation of mirth or joy, or, less commonly, sarcasm or scorn
Alternative medicine See Laughter club, Laughter therapy, Laughter yoga
Neurology Spasmodic and largely involuntary expirations often accompanied by inarticulate vocalisations, generally evoked by mirth
Physiology Laughter increases blood flow to the brain and activates neural networks—e.g., nucleus accumbens (NAcc) and amygdala. Functional MRI data suggests that the increase in blood flow to NAcc evoked by extreme humour is similar to that triggered by monetary gain or use of some addictive drugs; a key symptom of depression is the lack of a sense of reward from previously rewarding activities—e.g., humour
Psychiatry Laughter is regarded as the most effective coping skill for anxiety-panic disorders and may temporarily alleviate the symptoms of anxiety and depression
Segen's Medical Dictionary. © 2012 Farlex, Inc. All rights reserved.


A series of inarticulate sounds produced as an expression of emotion, usually happiness or mirth. The role of humor and laughter in promoting a positive attitude and health and in preventing the progress of some diseases has been documented esp. when it is combined with proven medical therapies.

compulsive laughter

Laughter without cause, occurring in certain psychoses, esp. schizophrenia.

pathological laughter

Uncontrolled laughter (occasionally accompanied by, or alternating with, uncontrolled crying), caused by pseudobulbar lesions of the brain. These lesions may result from lacunar strokes, multiple sclerosis, anoxic brain injury, and other forms of brain injury.
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
And he had to set straight yet another who had written: "This world is falling apart, Paul Chuckle has now died a year after his brother."
<B The Chuckle Brothers, Barry, left, and Paul Elliott - veteran entertainer Barry Chuckle has died at the age of 73 Yui Mok
They had started their careers as 'The Chuckles' on talent show Opportunity Knocks in 1967 before making their name with BBC show ChuckleVision in the 1980s and 1990s.
Ms Smith is a late night TV personality and international comedy performer, who performed for the Chuckle Club in July last year.
In order to create the best range of cards and the most dynamic site possible, Chuckle Monster has brought together a team of the industry's best illustrators, designers, artists and writers.
And help is at hand thanks to chuckle fest Comedy Port.
Overhead, early rising mallards made the soft "dug-a, dug-a, dug-a" chuckle and "ka, ka, kuk" clucks.
Summary: Chuckle brothers and sisters in Japan have guffawed their way through World Laughter Day.
Bush administration, all seven long plague years, a chuckle has always been in order, and this cartoon brings the laugh track home.