chrysiasis


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chrysiasis

 [krĭ-si´ah-sis]
1. deposition of gold particles in the tissues as a result of prolonged or excessive parenteral chrysotherapy, which commonly causes adverse reactions consisting primarily of dermatitis, stomatitis, or transient mild proteinuria; more serious toxicity involves the hematopoietic system, liver, kidney, eye (cornea, lens), or other vital organs.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

chry·si·a·sis

(kri-sī'ă-sis),
A permanent slate-gray discoloration of the skin and sclera resulting from deposition of gold in macrophages.
See also: chrysocyanosis.
[G. chrysos, gold]
Farlex Partner Medical Dictionary © Farlex 2012

chry·si·a·sis

(kris-ī'ă-sis)
A permanent slate-gray discoloration of the skin and sclera resulting from deposition of gold in the connective tissue of the skin and eye together with increased melanin formation after administration of gold.
Synonym(s): chrysoderma.
[G. chrysos, gold]
Medical Dictionary for the Health Professions and Nursing © Farlex 2012

chrysiasis 

A deposition of gold in tissues, especially the cornea and conjunctiva and the lens leading to cataract. It occurs as a result of prolonged gold therapy (e.g. gold tablets, which are occasionally used in the treatment of rheumatoid arthritis).
Millodot: Dictionary of Optometry and Visual Science, 7th edition. © 2009 Butterworth-Heinemann
References in periodicals archive ?
Less common adverse events include allergic reaction, darkening of cosmetic tattoos, immune reaction, and chrysiasis, which is a dark-blue pigmentation caused by Q-switched laser treatment in patients with a history of gold salt ingestion.
The pigment should be differentiated from melanin; chrysiasis; ochronosis; and tetracycline, antimalarial and amiodarone hyperpigmentation.
(22) Differential Diagnoses (29): Acquired bilateral nevus of Ota-like macules, Argyria, Addison's disease, Atopic dermatitis, Berloque dermatitis, Chronic actinic dermatitis, Chrysiasis, Contact dermatitis, Cutaneous lupus erythematosus, Drug-induced hyperpigmentation, Erythema dyschromicumperstans, Erythromelanosisfollicularisfaciei et colli, Exogenous ochronosis, Facial erythema abigne, Lentigo, Lichen planus, actinic type, Mastocytosis, Minocycline pigmentation, Photosensitivity reactions, Polymorphous light eruption, Poikiloderma of Civatte, Postinflammatory hyperpigmentation, Riehl'smelanosis, Skin infections
This side effect is called chrysiasis, (109) and has never been reported with the use of colloidal metallic gold.
Less common adverse effects include an allergic reaction, darkening of the cosmetic tattoo, an immune reaction, and chrysiasis, a dark-blue pigmentation caused by Q-switched laser treatment in patients with a history of gold-salt ingestion.