connective tissue disorders, acne, infection, inflammations, chronic venous stasis
, cutaneous neoplasm and trauma are the main etiologies of this condition2-4.
The verrucous plaques next to the ulcer were the result of chronic venous stasis
Santilli and his associates at the University of Minnesota, Minneapolis, used the system to treat 17 inpatients with a total of 31 chronic venous stasis
ulcers that had been present for more than 4 years.
Additionally, our partner in Europe, Sigma-Tau Group, is planning to conduct a Phase II study in Italy this year to evaluate TB4 for the treatment for chronic venous stasis
The secondary type of osteoma cutis--which our patient had--often arises within a cancerous lesion (especially melanocytic nevi and basal cell carcinoma) or chronic inflammation (as is found in traumatic scars, acne vulgaris, chronic venous stasis
, vasculitis, and other nonspecific inflammatory conditions).
Silverstein had previous experience utilizing OrCel in clinical trials for the treatment of donor sites in burn patients and chronic venous stasis
ulcers, and had been pleased with these results.
Silverstein has previous experience utilizing CCS in clinical trials for the treatment of donor sites in burn patients and chronic venous stasis
ulcers, and has been pleased with these results.