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In humans, chronic pancreatitis has been implicated in 3-4% of pancreatic cancers (Maisonneuve and Lowenfels 1999, 2002).
Of the 6 patients with chronic pancreatitis (all of whom underwent operations), conventional real-time PCR revealed the presence of KRAS mutations in 2 cases, and digital PCR also identified 2 cases as positive.
As stated earlier, the risk of alcoholic acute and chronic pancreatitis increases with increasing intake of ethanol.
Factors associated with health-related quality of life in chronic pancreatitis.
Advances in understanding the mechanisms leading to chronic pancreatitis.
At EUS and ERCP abnormalities suggestive of chronic pancreatitis were more common in high-risk patients than in control subjects.
Diabetes mellitus can be a complication of acute and chronic pancreatitis, though why this happens has yet to await explanation, and not too many studies exist to show new insights.
Acting on the observation that oxidative stress has been implicated in the pathophysiology of chronic pancreatitis CP), the authors evaluated the effects of antioxidant supplementation on pain relief, oxidative stress and antioxidant status in patients with CP.
A localised, paralytic intestinal loop ('sentinel loop'), paucity of air in the colon distal to the splenic flexure due to functional spasm of the descending colon ('colon cut-off sign'), pancreatic calcifications as seen in chronic pancreatitis, blurred margins of the psoas muscles or calcified biliary concrements can be indirect signs of pancreatitis.
They are reported to occur in 10% of chronic pancreatitis cases, with a high mortality rate after rupture.
hospitals are associated with chronic pancreatitis.

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