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glomerulonephritis that presents with persisting proteinuria, chronic renal failure, and hypertension, of insidious onset or as a late sequel of acute glomerulonephritis; the kidneys are symmetrically contracted and granular, with scarring and loss of glomeruli and the presence of tubular atrophy and interstitial fibrosis.
Synonym(s): chronic nephritis
Etymology: Gk, chronos, time, nephros, kidney, itis, inflammation
a form of kidney inflammation usually secondary to another disease, such as chronic pyelonephritis. In chronic interstitial nephritis the kidney becomes small and granular with thickening of arteries and arterioles and proliferation of interstitial tissue. There may be functional abnormalities, such as urea retention, hematuria, and casts.
chronic nephritis(1) Chronic glomerulonephritis, see there.
(2) A nonspecific term for any chronic inflammatory process arising in the kidney.