chronic necrotizing aspergillosis

chronic necrotizing aspergillosis

an indolent but slowly progressive infection of the lungs in patients with underlying lung disease, caused by aspergillus. Most affected patients have a modest depression of the immune system, caused by diseases such as diabetes.
Farlex Partner Medical Dictionary © Farlex 2012
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Table 1: Diagnostic criteria for chronic necrotizing aspergillosis. TABLE 1 Diagnostic criteria for chronic necrotising aspergillosis Diagnostic Characteristics criteria Clinical * Chronic (> 1 month) pulmonary or systemic symptoms, including at least one of: weight loss, productive cough or haemoptysis * No overt immunocompromising conditions (e.g.
Chronic necrotizing pulmonary aspergillosis (CNPA) is an uncommon invasive pulmonary infection with a slow and indolent course.4 We present a case of chronic necrotizing aspergillosis in a patient on immunosuppressive therapy due to renal transplantation.
For Aspergillus infections, the guidelines recommend intravenous voriconazole or liposomal amphotericin B for invasive pulmonary aspergillosis; voriconazole or itraconazole for mild to moderate chronic necrotizing aspergillosis; and liposomal amphotericin B or intravenous voriconazole for severe chronic necrotizing aspergillosis.

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