chronic myeloproliferative disorder


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chronic myeloproliferative disorder

A generic term for the autonomous proliferation of myelopoietic stem cells.

Chronic myeloproliferative disorders
• Common—Chronic myeloid leukaemia, polycythemia vera, essential thrombocythemia, chronic idiopathic myelofibrosis.
• Uncommon—Chronic neutrophilic leukaemia, chronic eosinophilic leukaemia/hypereosinophilic syndrome, chronic myeloproliferative disease, unclassifiable.
References in periodicals archive ?
Prevalence ofJAK2 V619F mutation in Indian patients with chronic myeloproliferative disorders.
JAK2 V617F mutation was detected in 68 per cent (51 of 75) patients with chronic myeloproliferative disorders.
The 2001 World Health Organization and updated European clinical and pathological criteria for the diagnosis, classification, and staging of the Philadelphia chromosome negative chronic myeloproliferative disorders.
Clinical utility of the absolute number of circulating CD34-positive cells in patients with chronic myeloproliferative disorders.
Soluble angiogenic factors: implications for chronic myeloproliferative disorders.
Comparison of molecular markers in a cohort of patients with chronic myeloproliferative disorders.
Chronic myeloproliferative disorders (MPDs) include polycythemia vera, chronic myelocytic leukemia, essential thrombocythemia, and myelofibrosis with myeloid metaplasia.
To make a definitive diagnosis of Gaucher disease, assays for acid [Beta]-glucosidase activity in white blood cells or fibroblasts must be performed, because Gaucher-like cells may be found in patients with other conditions, such as chronic myeloproliferative disorders, chronic dyserythropoietic anemias, thalassemia, Shwachman syndrome (overloading of normal enzymatic capacity to process normal cell breakdown), or other malignant conditions.
Chronic myeloproliferative disorders (CMPDs) are a group of heterogeneous clonal stem cell disorders that can be defined by specific cytomorphological phenotypes and sometimes genetic features (1).

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