chronic leg ulcer

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a local defect, or excavation of the surface of an organ or tissue, produced by sloughing of necrotic inflammatory tissue.
aphthous ulcer a small painful ulcer in the mouth, approximately 2 to 5 mm in diameter. It usually remains for five to seven days and heals within two weeks with no scarring.
chronic leg ulcer ulceration of the lower leg caused by peripheral vascular disease involving either arteries and arterioles or veins and venules of the affected limb. Arterial and venous ulcers are quite different and require different modes of treatment. Venous stasis ulcers occur as a result of venous insufficiency in the lower limb. The insufficiency is due to deep vein thrombosis and failure of the one-way valves that act during muscle contraction to prevent the backflow of blood. Chronic varicosities of the veins can also cause venous stasis.

Patient Care. Stasis ulcers are difficult to treat because impaired blood flow interferes with the normal healing process and prolongs repair. Patient care is concerned with preventing a superimposed infection in the ulcer, increasing blood flow in the deeper veins, and decreasing pressure within the superficial veins.
decubitus ulcer pressure ulcer.
duodenal ulcer an ulcer of the duodenum, one of the two most common types of peptic ulcer.
gastric ulcer an ulcer of the inner wall of the stomach, one of the two most common kinds of peptic ulcer.
Hunner's ulcer one involving all layers of the bladder wall, seen in interstitial cystitis.
hypertensive ischemic ulcer a manifestation of infarction of the skin due to arteriolar occlusion as part of a longstanding vascular disease, seen especially in women in late middle age, and presenting as a red painful plaque on the lower limb or ankle that later breaks down into a superficial ulcer surrounded by a zone of purpuric erythema.
marginal ulcer a peptic ulcer occurring at the margin of a surgical anastomosis of the stomach and small intestine or duodenum. Marginal ulcers are a frequent complication of surgical treatment for peptic ulcer; they are difficult to control medically and often require further surgery.
peptic ulcer see peptic ulcer.
perforating ulcer one that involves the entire thickness of an organ, creating an opening on both surfaces.
phagedenic ulcer
1. any of a group of conditions due to secondary bacterial invasion of a preexisting cutaneous lesion or the intact skin of an individual with impaired resistance as a result of a systemic disease, which is characterized by necrotic ulceration associated with prominent tissue destruction.
pressure ulcer see pressure ulcer.
rodent ulcer ulcerating basal cell carcinoma of the skin.
stasis ulcer ulceration on the ankle due to venous insufficiency and venous stasis.
stress ulcer a type of peptic ulcer, usually gastric, resulting from stress; possible predisposing factors include changes in the microcirculation of the gastric mucosa, increased permeability of the gastric mucosa barrier to H+, and impaired cell proliferation.
trophic ulcer one due to imperfect nutrition of the part.
tropical ulcer
1. a lesion of cutaneous leishmaniasis.
tropical phagedenic ulcer a chronic, painful phagedenic ulcer usually seen on the lower limbs of malnourished children in the tropics; the etiology is unknown, but spirochetes, fusiform bacilli, and other bacteria are often present in the developing lesion, and protein and vitamin deficiency with lowered resistance to infection may play a role in the etiology.
varicose ulcer an ulcer due to varicose veins.
venereal ulcer a nonspecific term referring to the formation of ulcers resembling chancre or chancroid about the external genitalia; there are both sexually transmitted and other types.
Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

chronic leg ulcer

Any long-standing, slowly healing ulcer of a lower extremity, esp. one caused by occlusive disease of the arteries or veins or by varicose veins.
See also: ulcer
Medical Dictionary, © 2009 Farlex and Partners
References in periodicals archive ?
Evidence-based treatment of chronic leg ulcers. Deutsches Arzteblatt Int.
* Factors associated with malignancy in chronic leg ulcers include older age, abnormal excessive granulation tissue at wound edges, high clinical suspicion of cancer, and number of previous biopsies.
Also reported were 16 (12.8%) patients with diabetes mellitus, 10 (8.0%) with liver disease, 14 (11.2%) with venous insufficiency, and 7 (5.6%) with chronic leg ulcers. Forty patients (32.0%) had received antibiotics within the month prior to presentation, 50 (40.0 %) reported a SSTI within a year prior to presentation, and 18 (14.4%) had recent surgery in infection.
The patient is a 56-year-old African-American male with homozygous sickle cell disease with chronic leg ulcers for more than 10 years.
Many techniques have been tried over the centuries to heal chronic leg ulcers. Recent studies have shown that application of a sub-atmospheric pressure in a controlled manner to the wound site has an important role in assisting wound healing.
These patients also experience chronic leg ulcers, facial dysmorphism, and mental retardation.
In clinics across Europe and Israel, the BRH-A2 has shown effectiveness at healing chronic leg ulcers and diabetic foot ulcers.
After the discovery of inhibin, honey use was started widely for chronic wounds, burns, chronic leg ulcers, decubitus ulcers and radiation necrosis.
Miller cited a recent study of 142 patients and 169 limbs with chronic leg ulcers. These patients could not be treated with revascularization surgery due to comorbidities and other risk factors (J.
Miller cited a recent study of 142 patients and 169 limbs in which chronic leg ulcers were treated with pressure relief, debridement, infection control, and moist healing.
A number of factors have been found which were associated with the healing of these chronic leg ulcers. We examined those related to venous disease in the expectation that these are important in the healing process.
[3] Chronic leg ulcers (CLU) affect 0.6%-3% of those aged over 60 years, increasing to over 5% of those aged over 80 years.

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