chronic hypoxia

chronic hypoxia

a usually slow, insidious reduction in tissue oxygenation resulting from gradually destructive or fibrotic lung diseases, congenital or acquired heart disorders, or chronic blood loss. The patient experiences persistent mental and physical fatigue, shows sluggish mental responses, and complains of a loss of ability to perform physical tasks. Unless treated, the condition may lead to disability. There may be some physiological adjustment to the lack of oxygen as occurs in individuals who move from sea level to mountainous areas, where oxygen pressures are reduced. Compare acute hypoxia.
References in periodicals archive ?
In our previous study, we found that IUGR as a result of undernutrition is related to chronic hypoxia pulmonary arterial hypertension (CH-PAH) in adulthood, while the smooth muscle layer undergoes remodeling (2,9).
This chronic hypoxia can lead to or aggravate multiple medical problems including heart problems, sleep apneas, diabetes, hypertension, arteriosclerosis and sexual dysfunction.
5,18,19,39) Some authors conclude that vascular dilatation rather than proliferation is an adaptive change to chronic hypoxia.
Chronic hypoxia of various degrees was observed in 22 infants (44%).
Chronic hypoxia promoted the onset of a highly proinflammatory gene expression profile in mature DCs generated from human monocytes [34].
This dose of rats was converted based on previous work where daily dose of sRAGE in a mouse model of chronic hypoxia was 20 [micro]g/day [24].
One change that occurs across many different animal groups in response to chronic hypoxia is an increase in the concentration of respiratory pigment, but the concentration of hemocyanin within an individual crustacean can vary depending on life-history factors such as molt cycle, life stage, sex, and size, as well as environmental factors such as ambient oxygen concentration, season, salinity, and diet (reviewed in Giomi and Beltramini, 2007).
Chronic hypoxia present in anemia is a causative factor for worsening cardiovascular health in patients with CKD.
Therefore cognitive dysfunction in diabetes patients may be closely associated with hyperglycemia and chronic hypoxia in tissue.
Additionally, the impact of chronic hypoxia on the human body and its adaptation processes have been investigated extensively; however, only a few papers were found about the impact of acute normobaric hypoxia (Benoit et al.

Full browser ?