chronic active hepatitis


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Related to chronic active hepatitis: hepatitis, Chronic Persistent Hepatitis

chron·ic act·ive hep·a·ti·tis

hepatitis with chronic portal inflammation that extends into the parenchyma, with piecemeal necrosis and fibrosis that usually progresses to a coarsely nodular postnecrotic cirrhosis.

chronic active hepatitis (CAH)

a potentially fatal form of hepatitis complicated by portal inflammation and extending into the parenchyma. There may be progressive destruction of the liver lobule with necrosis and fibrosis leading to scarring and cirrhosis. Possible causes include viral infections, drugs, and autoimmune reactions.

chronic active hepatitis

1. Obsolete term. See Chronic hepatitis.
2. Chronic viral hepatitis.

chron·ic act·ive hep·a·ti·tis

(kronik aktiv hep-ă-tītis)
Liver disease with portal inflammation that extends into the parenchyma, and usually progresses to a coarsely nodular postnecrotic cirrhosis.

hepatitis

inflammation of the liver which may be toxic or infectious in origin; characterized by signs due to diffuse injury to the liver. See also liver dysfunction. There are a number of etiologically specific hepatitides which are listed under their individual headings. They are avian vibrionic hepatitis, infectious canine hepatitis (see below), infectious necrotic hepatitis, duck hepatitis, turkey hepatitis, inclusion body hepatitis, mouse hepatitis, postvaccinal hepatitis, toxemic jaundice, and those caused by fasciola and fascioloides, cysticercus, and plant toxins including pyrrolizidine alkaloids, sporidesmin, aflatoxin. See also hepatosis dietetica.

hepatitis A, B, C, D and E viruses
causes of hepatitis in humans and some nonhuman primates.
avian vibrionic hepatitis
a disease of domesticated poultry which has disappeared from those areas in the USA which were its sole habitat. Vibrio-like organisms were isolated from the outbreaks which occurred.
cholangiolitic hepatitis
chronic active hepatitis
a chronic inflammatory liver disease in humans, probably of several types with different causes, but with distinctive histopathological features of piecemeal necrosis, bridging fibrosis and active cirrhosis. A similar, but not identical disease of unknown etiology has been described in dogs.
copper-induced hepatitis
see bedlington terrier copper-associated hepatopathy.
duck hepatitis
see duck hepatitis.
gosling hepatitis
see goose hepatitis.
infectious canine hepatitis
an acute, highly contagious disease, occurring mainly in young dogs, caused by canine adenovirus type 1. Many dogs experience subclinical infections. Those with clinical signs show fever, depression, vomiting and abdominal pain. The course is short and in severe cases death occurs within a few days. Peracute infections occur in very young puppies. Mild infections may cause only vague signs of malaise and anorexia and many cases are not diagnosed. Dogs recovering from infection sometimes develop corneal edema ('blue eye'). A chronic hepatitis is reported as an occasional sequela. The disease can be prevented by vaccination.
mouse hepatitis
a coronavirus disease which causes heavy losses in baby mice. It is characterized by tremor, jaundice and hemoglobinuria.
mycotic hepatitis
commonly caused in cattle by extension from mycotic rumenitis due to lactic acid indigestion and damage to ruminal epithelium.
necrotic hepatitis
see infectious necrotic hepatitis.
porcine hepatitis E virus
an enteric virus of pigs related to human hepatitis E that is not known to be pathogenic.
toxipathic hepatitis
hepatitis caused by toxins, especially ingested plant toxins, e.g. some pyrrolizidine alkaloids, sporidesmin, aflatoxin.
trophopathic hepatitis
see trophopathic hepatitis.
turkey hepatitis
see turkey hepatitis.
hepatitis X
a hepatoxic disease of dogs and pigs caused by aflatoxins. See also mycotoxicosis.
References in periodicals archive ?
Corticosteroids, immunosuppressant drugs, and alpha-interferon may be prescribed to treat chronic active hepatitis C.
Retinal complications with elevated circulating plasma C5a associated with interferon-alpha therapy for chronic active hepatitis C.
Chronic active hepatitis (CAH) is defined as symptomatic with biochemical or serological evidence of continuing or relapsing hepatic disease for more than six months with histologically documented inflammation, necrosis and eventually fibrosis.
Tissue-inhibitors of metal loproteinases in liver and serum/plasma in chronic active hepatitis C and HCV-induced cirrhosis.
Miss Passey's was diagnosed with chronic active hepatitis at the age of eight.
19 Numerous studies worldwide suggest that hepatitis B viral infection has the capacity to confer on perinatally infected infants a high likelihood of such significant chronic sequelae as chronic active hepatitis, cirrhosis, and hepatocelluar carcinoma.
In Taiwan and China, ABI's Taiwanese partners are expected to conduct a clinical trial in chronic active hepatitis C patients.
she had strong AMA +ve titres (1:1000) in view of autoimmune etiology she was subjected to liver biopsy which revealed chronic active hepatitis (HA1-3).
Prevention of hepatocellular carcinoma in patients with chronic active hepatitis C and cirrhosis.
Four years ago Miss Sally Passey, aged 23, underwent a life-saving liver transplant to alleviate chronic active hepatitis.
More common is chronic active hepatitis, with its long-term debilitating sequelae.
Nasdaq:AVII) reported results today from the second phase of its multicenter study in patients with chronic active hepatitis C virus (HCV) infection.

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