chronic actinic dermatitis


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chronic actinic dermatitis

A photosensitive dermopathy that occurs in all races, which primarily affects elderly men, and may be linked to endogenous eczema, photoallergic or allergic contact dermatitis, drug photosensitivity, polymorphic light eruption or, rarely, HIV infection.

Chronic actinic dermatitis, key features
• Reduction in the minimal erythema dose to UVA, UVB and/or visible light;
• Persistent eczematous eruption that predominantly affects sun-exposed skin, but which may extend to covered areas;
• Histopathologic changes consistent with chronic eczema ± cutaneous lymphoma-like changes.
References in periodicals archive ?
Patients with chronic actinic dermatitis usually present with persistent erythematous skin lesions on the face and all other sun-exposed surfaces.
In milder cases, the lesions of chronic actinic dermatitis can be cleared using topical tacrolimus or topical corticosteroids.
There are reports of treatment of eczema with immunosuppressive drugs such as cyclophosphamide6 and azathioprine.7,8 Limited open studies suggest that azathioprine may be effective in controlling chronic actinic dermatitis.9,10
Patients of either sex, presenting to our department, clinically suggestive of having chronic actinic dermatitis were enrolled.
Azathioprine produced an objective response in all but one of our patients with chronic actinic dermatitis. Six (40%) of the 15 patients showed near complete clearance i.e.

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