Two parameters related to excitability were measured: rheobase and chronaxy. The rheobase of the DB8 and DB12 groups had a significant increase of 7.9% and 14.4%, respectively, compared to rheobase that was observed in the respective E groups (3.4 [+ or -] 0.09 V and 3.45 [+ or -] 0.09 V vs 3.01 [+ or -]0.09 V and 3.15 [+ or -]0.06 V, respectively).
In the STZ-induced diabetes model used herein, both chronaxy and rheobase were increased in the SN.
The electrophysiological parameters PPA, conduction velocity of CAP first and second components, rheobase, and chronaxy
were analyzed after nerve stabilization and the control values were 7.1 [+ or -] 0.27 mV, 85.4 [+ or -] 2.34 m/s, 30.8 [+ or -] 1.11 m/s, 3.4 [+ or -] 0.22 V, and 51.5 [+ or -] 2.34 ms (n=87), respectively.