WLS(redirected from chromosome 1 open reading frame 139)
WLSA gene on chromosome 1p31.3 that encodes a G protein-coupled receptor which regulates the sorting and secretion of Wnt proteins by a feedback regulatory mechanism. WLS plays a key role in regulating expression, subcellular location, binding and organelle-specific association of Wnt proteins, and plays a key role in establishing anterior-posterior body axis formation during development.
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