chromosomal

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chro·mo·som·al

(krō'mō-sō'măl),
Pertaining to chromosomes.

chromosomal

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chro·mo·som·al

(krōmŏ-sōmăl)
Pertaining to chromosomes.

chromosomal,

adj relating to chromosome, or a configuration within the cell's nucleus that contains a linear thread of DNA that conveys genetic data.

chromosomal

emanating from or pertaining to chromosome.

chromosomal aberration
see chromosomal abnormality (below).
chromosomal abnormality
abnormal karyotype; abnormalities can be detected before birth by means of amniocentesis, or after birth, but many are probably never observed because they cause death and disposal of the fetus. The abnormalities are either of number, or of composition of the individual chromosomes. Monosomy and trisomy are examples of numerical abnormalities. Translocations are examples of abnormalities of structure where parts of one chromosome have been transferred to another. The cause of these abnormalities is not known. Their importance is that many of them are linked with structural or functional defects of the animal body. The best known ones in veterinary medicine are those that are related to infertility, e.g. translocation 1/29, translocation 27/29.
chromosomal analysis
fetal cells obtained by amniocentesis or lymphocytes from a blood sample can be cultured in the laboratory until they divide. Cell division is arrested in mid-metaphase by the drug Colcemid, a derivative of colchicine. The chromosomes can be stained by one of several techniques that produce a distinct pattern of light and dark bands along the chromosomes, and each chromosome can be recognized by its size and banding pattern. The chromosomal characteristics of an animal are referred to as its karyotype. This also refers to a photomicrograph of a cell nucleus that is cut apart and rearranged so that the individual chromosomes are in order and labeled. The autosomes are numbered roughly in order of decreasing length. The sex chromosomes are labeled X and Y. Karyotyping is useful in determining the presence of chromosome defects.
chromosomal banding
see banding (2).
chromosomal chimerism
see chimera.
chromosomal crossover
chromosomal deletion
in genetics, loss from a chromosome of genetic material.
chromosomal inversion
see inversion (2).
chromosomal linkage
see linkage (2).
chromosomal mapping
see genetic map.
chromosomal non-disjunction
failure of the chromatids or chromosomes to separate (disjoin) during meiosis.
chromosomal replication
chromosomal walking
a technique for identification and isolation of contiguous sequences of genomic DNA.
chromosomal X inactivation
only one of a pair of female (X) chromosomes in the one cell is active, the other is inactivated.
References in periodicals archive ?
Genetics of chromosomally mediated intermediate resistance to ceftriaxone and cefixime in Neisseria gonorrhoeae.
However the evidence suggests that the chances of such an embryo forming a successful pregnancy are considerably less than those of a chromosomally normal embryo.
An oft-cited example of ongoing chromosomally mediated speciation is the Sceloporus grammicus complex of central Mexico (White 1978; Hall 1983; King 1993).
hispidus appears to be the most chromosomally divergent species examined.
Likewise, second day intracytoplasmic sperm injection in these same high risk patients failed to yield chromosomally normal embryos; suggesting that the technique of second day ICSI should not be employed with patients with high risk.
Although the exact mechanism of metronidazole resistance is unknown, it has been attributed to chromosomally or plasmid-encoded nitroimidazole resistance (nim) genes encoding nitroimidazole reductase (8-10).
The cost of infertility treatment in such an equation basically costs out at zero for couples who decide to transfer only one chromosomally selected embryo, said Dr.
The most common chromosome abnormality in RM couples is a balanced translocation, including reciprocal and Robertsonian translocations, which allow a normal parental phenotype but chromosomally unbalanced gametes.
She was a chromosomally XX female but with masculine gonads (cryptorchid testicles) due to the presence of other genes that determined the formation of testicles in the absence of the genes present on the Y chromosome," said Campos.
Beta-lactamase plasmids and chromosomally mediated antibiotic resistance in pathogenic Neisseria species.
We present data showing that (a) methylation-sensitive amplification can be performed on very small (approximately 1 ng) DNA samples and the difference in methylation between 2 DNA samples as determined by microarray analysis is well validated by bisulfite PCR analysis; and (b) methylation-sensitive amplification followed by microarray analysis can be used to confidently detect whole-chromosome aneuploidy in first-trimester TB DNA samples that have been mixed with 90% chromosomally normal DNA from peripheral blood (PB) leukocytes.

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