chromosomal deletion


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Related to chromosomal deletion: Chromosomal inversion

chro·mo·som·al de·le·tion

a microscopically evident loss of part of a chromosome.
See also: monosomy.

chro·mo·som·al de·le·tion

(krō'mŏ-sō'măl dĕ-lē'shŭn)
A microscopically evident loss of part of a chromosome.
See also: monosomy
References in periodicals archive ?
We argue that chromosomal deletion is a major feature of karyotypic changes in Pectinidae, as indicated by the wide range of chromosomal arms (19-38, Table 3) and DNA contents (2.23-3.28 pg per diploid genome) (Rodriguez-Juiz et al., 1996; Gonzales-Tizon et al., 2000; Thiriot-Quievreux, 2002).
"We'd like to look for uniparental disomy in many of the large number of syndromes we believe are inherited but that don't show evidence of chromosomal deletions," says Judith G.
It has increased the identification and resolution of large chromosomal deletions, duplications and rearrangements, typically involving a number of genes.
The improvements in sleep quality and sleep duration demonstrated in the 2401 study were consistent across patients with chromosomal deletions of various lengths as well as a single patient with a point mutation in the RAI1 gene on chromosome 17p.
His past medical history was significant for newly diagnosed chronic lymphocytic leukemia (CLL) with 17p chromosomal deletions. At the time of CLL diagnosis, he had palpable lymphadenopathy in the left posterior cervical triangle, both axillae, and significant pelvic lymphadenopathy causing bladder obstruction requiring catheterization.
It offers hope for the most difficult-to-treat people with various chromosomal deletions that normally do very badly or are resistant to chemotherapy.