chromophobic


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Related to chromophobic: chromophobic adenoma

chro·mo·phobe

(krō'mō-fōb),
Resistant to stains, staining with difficulty or not at all; denoting certain degranulated cells in the anterior lobe of the pituitary gland.
Synonym(s): chromophobic
[chromo- + G. phobos, fear]

chromophobic

[krō′məfō′bik]
denoting a cell, tissue, or microorganism that is not easily stained, particularly certain cells of the anterior lobe of the pituitary gland. Compare chromophilic.

chro·mo·phobe

(krō'mō-fōb)
Resistant to stains, staining with difficulty or not at all; denoting certain degranulated cells in the anterior lobe of the pituitary gland.
Synonym(s): chromophobic.
[chromo- + G. phobos, fear]

chromophobia

(krō″mō-fō′bē-ă)
The condition of staining poorly.
chromophobic (-bĭk), adjective
References in periodicals archive ?
TK1s may indicate some favorable effects on metastatic chromophobic RCCs (specifically achieved with sunitinib); however, no significant effect was observed on metastatic papillary RCCs.
Such histologic distinctions take on an especial importance when considering that the clear cell morphology common to the renal tumors seen in von Hippel-Lindau syndrome or the chromophobic or oncocytic features frequently noted in the renal tumors of Brit-Hogg-Dube syndrome may aid in distinguishing these entities from renal PNET.
These problems preclude its routine use in clinical practice, in that a negative biopsy does not exclude cancer, and also because of the difficulty for pathologists to distinguish between chromophobic RCC and oncocytoma.
The histologic diagnosis of pituitary adenomas classifies tumors as acidophilic, basophilic, and chromophobic using conventional stains; acidophilic adenomas were said to be associated with acromegaly or gigantism, basophilic adenomas were thought to be the cause of Cushing disease, and chromophobic tumors were considered to be nonfunctioning from the endocrine perspective.