chromophobic

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Related to chromophobic: chromophobic adenoma

chro·mo·phobe

(krō'mō-fōb),

Resistant to stains, staining with difficulty or not at all; denoting certain degranulated cells in the anterior lobe of the pituitary gland.

Synonym(s): chromophobic

[chromo- + G. phobos, fear]

chro·mo·phobe

(krō'mō-fōb)

Resistant to stains, staining with difficulty or not at all; denoting certain degranulated cells in the anterior lobe of the pituitary gland.
Synonym(s): chromophobic.

[chromo- + G. phobos, fear]

chromophobia

(krō″mō-fō′bē-ă)

The condition of staining poorly.

chromophobic (-bĭk), adjective

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References in periodicals archive ?

In addition, expression profiles in chromophobic RCC samples were markedly greater than that of clear cell and papillary subtypes.

These findings could explain the good prognosis that is implied by higher levels of miR-34a in the current samples with low pathological grade and in chromophobic RCC subtype.

Further functional studies are recommended to unravel the molecular mechanisms underlying the chromophobic RCC which has the best prognosis among all other subtypes in our cases [58-60].

In addition, strong staining was correlated with chromophobic RCC subtype.

Higher protein level expression was associated with poor tumor differentiation and chromophobic subtype.

Absent staining of Tp53 protein in tumor cell nuclei was significantly associated with advanced pathological grade, while positive staining was observed in the chromophobic RCC, known to have the best prognosis.

Furthermore, chromophobic RCC subtype has been postulated to attain different transcriptomics and proteomics characteristics compared to other subtypes.

MicroRNA-34a: A Key Regulator in the Hallmarks of Renal Cell Carcinoma

TK1s may indicate some favorable effects on metastatic chromophobic RCCs (specifically achieved with sunitinib); however, no significant effect was observed on metastatic papillary RCCs.

Tyrosine kinase inhibitors for the treatment of metastatic renal cell carcinoma: what urologists should know? / Metastatik renal hucreli karsinom tedavisinde tirozin kinaz inhibitorleri: Urologlar ne bilmelidir?

(3) Other subtypes of RCC include chromophobic, papillary, collecting duct, and RCC unclassified.

Prognostic significance of CD44, platelet-derived growth factor receptor [alpha], and cyclooxygenase 2 expression in renal cell carcinoma