chromophobe renal cell carcinoma

(redirected from chromophobe cell carcinoma)

chromophobe renal cell carcinoma

a low-grade renal cell carcinoma composed of large polygonal cells with well-defined borders and amphophilic or pale cytoplasm. These cells grow in solid sheets, but focally they may form tubules, trabeculae, or cysts.

chromophobe renal cell carcinoma

An uncommon (4–5% of all renal tumours) renal cell carcinoma with relatively indolent growth and histologic changes of renal oncocytoma. It is thought to arise in the intercalated cells of the collecting ducts.

DiffDx
Oncocytoma, renal cell carcinoma—granular cell type.
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References in periodicals archive ?
GHG in granular cell carcinoma, chromophobe cell carcinoma, oncocytoma of the kidney.
Renal chromophobe cell carcinoma and oncocytoma: a comparative morphologic, histochemical, and immunohistochemical study of 124 cases.
[6] Chromophobe cell carcinoma accounts for only 3-5% of all RCCs and carries a better prognosis than clear cell RCC.
The most common renal malignancy in adult is clear cell carcinoma followed by papillary carcinoma and chromophobe cell carcinoma (5,6).
Immunohistochemical analysis for cytokeratin 7, KIT, and PAX2: value in the differential diagnosis of chromophobe cell carcinoma. Am J Clin Pathol.
Chromophobe cell carcinoma of the kidney: a clinicopathologic study of 21 cases.
In 2 cases, the largest tumor was a renal chromophobe cell carcinoma. The authors also described hybrid tumors composed of typical oncocytic cells and chromophobe cells.