chromophobe renal cell carcinoma

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Related to chromophobe carcinoma: chromophobe renal cell carcinoma, renal cell carcinoma chromophobe type, chromophobe RCC

chromophobe renal cell carcinoma

a low-grade renal cell carcinoma composed of large polygonal cells with well-defined borders and amphophilic or pale cytoplasm. These cells grow in solid sheets, but focally they may form tubules, trabeculae, or cysts.

chromophobe renal cell carcinoma

An uncommon (4–5% of all renal tumours) renal cell carcinoma with relatively indolent growth and histologic changes of renal oncocytoma. It is thought to arise in the intercalated cells of the collecting ducts.

DiffDx
Oncocytoma, renal cell carcinoma—granular cell type.
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Mostly sarcomatoid carcinomas are found in association with conventional (clear cell) renal carcinoma, but there are occasional descriptions of sarcomatoid transformation of chromophobe carcinoma,[8,9] collecting duct carcinoma,[10] and papillary carcinoma.
Additional histochemical stains of periodic acid-Schiff and Hale's colloidal iron were available for chromophobe carcinomas.