chromoblastomycosis


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Related to chromoblastomycosis: sporotrichosis

chromoblastomycosis

 [kro″mo-blas″to-mi-ko´sis]
a chronic fungal infection of the skin, usually beginning at the site of a puncture wound or other trauma on one leg or foot, but sometimes involving other areas of the body, with wartlike nodules or papillomas that may or may not ulcerate. It is usually caused by Phialophora verrucosa, Fonsecaea compactum, F. pedrosoi, or Cladosporium carrionii. Called also chromomycosis and verrucose or verrucous dermatitis.

chro·mo·blas·to·my·co·sis

(krō'mō-blas'tō-mī-kō'sis),
A localized chronic mycosis of the skin and subcutaneous tissues characterized by skin lesions so rough and irregular as to present a cauliflowerlike appearance; caused by dematiaceous fungi such as Phialophora verrucosa, Exophiala (Wangiella) dermatitidis, Fonsecaea pedrosoi, F. compacta, and Cladosporium carrionii; fungal cells resembling copper pennies form rounded sclerotic bodies in tissue, with epidermal hyperplasia and intraepidermal microabscesses.
Synonym(s): chromomycosis
[chromo- + G. blastos, germ, + mykē, fungus, + -osis, condition]

blastomycosis

A suppurative granulomatous infection caused by Blastomyces dermatitidis which may disseminate from an inoculation site—cut, bruise or scrape—leaving a central scar, mimicking skin cancer.
 
At risk
Immunocompromised patients—e.g., with AIDS—are at increased risk for disseminated blastomycosis.

Epidemiology
± 4/100,000 symptomatic, many more asymptomatic.
 
Clinical-systemic
Usually acquired by inhalation, may produce dermatitis, pneumonitis or present as a systemic disease in the skin, lungs, bones, liver, spleen or CNS. Usually begins as a respiratory infection, accompanied by cough, pleuritic chest pain, adult respiratory distress syndrome (ARDS), chills, malaise, anorexia and/or weight loss.

Management
Amphotericin B, especially for immunocompromised patients; itraconazole is the drug of choice for nonlife-threatening, non-CNS blastomycosis.

chromoblastomycosis

Chromomycosis Infectious disease An infection by various dematiaceous fungi: Fonsecaea pedrosoi, F compacta, Phialophora verrucosa, Cladosporium carrionii, Rhinocladiella aquaspersa Epidemiology Most US infections occur in whites, age 30–50, who are farmers or manual laborers Clinical Verrucoid, ulcerated, crusted lesions with pseudoepitheliomatous hyperplasia, keratolytic microabscesses. Cf Blastomycosis, Phaeohyphomycosis.

chro·mo·blas·to·my·co·sis

(krō'mō-blas'tō-mī-kō'sis)
A localized chronic mycosis of the skin and subcutaneous tissues characterized by skin lesions so rough and irregular as to present a cauliflowerlike appearance; caused by dematiaceous fungi such as Phialophora verrucosa, P. dermatitidis, Fonsecaea pedrosoi, F. compacta, and Cladophialophora carrionii; fungal cells resembling pennies form rounded sclerotic bodies in tissue, with epidermal hyperplasia and intraepidermal microabscesses.
Synonym(s): chromomycosis.
[chromo- + G. blastos, germ, + mykē, fungus, + -osis, condition]

chromoblastomycosis

A deep fungus tropical infection of the skin, usually on the foot, caused by a variety of fungi, and acquired on splinters of decaying wood. There are warty nodules that may ulcerate. The condition is very persistent. It is also known as chromomycosis.
References in periodicals archive ?
The chromoblastomycosis treatment market is projected to grow at a CAGR of around 6.3% during the forecast period 2017-2023.
We are emphasizing on the fact that consciousness about chromoblastomycosis among clinicians as well as pathologists could simplify the management strategy and provide relief from mental stress to the patients as well as the relatives.
In chromoblastomycosis there are characteristic sclerotic bodies which can be single or clusters and they are also called "copper penny lesions" which may show internal septation.
Chromoblastomycosis: clinical and mycologic experience of 51 cases.
The above-mentioned systemic therapy is the treatment procedure for Chromoblastomycosis. Surgery, cryotherapy and thermotherapy are also advised in combination with chemotherapy.(9) Potassium iodide can also be given for treatment.(10) Good hygiene and adequate nutrition may help the individual abort a potential infection.
Evaluation of the ELISA technique for the diagnosis and the seroepidemiology of chromoblastomycosis. J.
Chromoblastomycosis, dematiaceous fungi, skeletal involvement.
Cerebral chromoblastomycosis due to cladosporium trichoides (bantianum) part I.
(3-9) Clinical differential diagnosis includes the nodular variant of chromoblastomycosis, keloids, xanthomas, fibromas, Kaposi's sarcoma, neurofibromas and dermatofibrosarcoma protuberans.
Soft tissue fungal infections have also been documented among persons who were not directly injured during a disaster but who sustained minor trauma while performing post-disaster tasks: in Texas after Hurricane Ike in 2008, chromoblastomycosis was diagnosed in 3 patients, all of whom had histories of cancer and all of whom described clearing brush and fallen trees near their homes after the storm (8).
Ajoene and 5-Fluorouracil in the topical treatment of Cladophialophora carrionii chromoblastomycosis in humans: a comparative open study.
In such cases, the differential diagnosis includes lichen simplex chronicus, mycetoma, chromoblastomycosis, and squamous cell carcinoma.