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Pertaining to chromatography.
Farlex Partner Medical Dictionary © Farlex 2012


Pertaining to chromatography.
Medical Dictionary for the Health Professions and Nursing © Farlex 2012


(kro?ma-tog'ra-fe) [ chrom- + -graphy]
The separation of two or more chemical compounds in a liquid or gaseous mixture by their removal at different rates based on differential solubility and adsorption. This separation is often accomplished by letting the chemicals percolate through a column of a powdered adsorbent or by passing them across the surface of an adsorbent paper, among other techniques.chromatographic (-mat?o-graf'ik), adjective

adsorption chromatography

Chromatography accomplished by applying the test material to one end of a sheet or column containing a solid. As the material moves, the various constituents adhere to the surface of the particles of the solid at different distances from the starting point according to their chemical characteristics.

column chromatography

A form of adsorption chromatography in which the adsorptive material is packed into a column.

gas chromatography

An analytical technique in which a sample is separated into its component parts between a gaseous mobile phase and a chemically active stationary phase.

gas-liquid chromatography

Abbreviation: GLC
Chromatography in which a gas moves over a liquid, and chemical substances are separated on the liquid by their different adsorption rates.

gel filtration chromatography

A type of column chromatography in which chemicals are separated via pores according to their molecular size.

high-performance liquid chromatography

Abbreviation: HPLC
Application of high pressure to liquid chromatography technique to increase separation speed and enhance resolution.
Synonym: high pressure liquid chromatography

high pressure liquid chromatography

High-performance liquid chromatography.

paper chromatography

Chromatography in which paper strips are used as the porous solid medium.

partition chromatography

Chromatography in which substances in solution are separated by being exposed to two immiscible solvents. The immobile solvent is located between the spaces of an inert material such as starch, cellulose, or silica. The substances move with the mobile solvent as it passes down the column at a rate governed by their partition coefficient.

thin-layer chromatography

Abbreviation: TLC
Chromatography involving the differential adsorption of substances as they pass through a thin layer or sheet of cellulose or some other inert compound.
Medical Dictionary, © 2009 Farlex and Partners
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As a result, all endogenous amino compounds produce fluorescent derivatives, which produce very large solvent peaks, decreasing the sensitivity and increasing the length of the chromatographic run times.
In order to realize the chemical composition change in chromatographic peak of fingerprints, the sample from medicinal materials to pharmaceutical preparations using the same HPLC condition as fingerprint except mobile phase of 0.1% formic acid instead of 0.1% phosphoric acid by LC/QTOF-MS.
However, traditional high-performance liquid chromatography (HPLC) instrumentation can deleteriously impact the observed chromatographic efficiency.
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According to the International Union of Pure and Applied Chemistry (1), affinity chromatography is defined as a liquid chromatographic technique that makes use of a "biological interaction" for the separation and analysis of specific analytes within a sample.
Its chromatographic profile shows that AUC of the caffeine is 414079 and that of IS is 1487033 (figure
[12], liquid chromatographic determination of levamisole in animal plasma by Baere S et al.
Due to the basic character of isoquinoline alkaloids, it would be preferable to conduct chromatographic separation at alkaline pH to avoid their ionization; however, silica-based adsorbents are unstable at this condition [21].
Summary: A high performance liquid chromatographic method was developed and validated to simultaneously quantify citalopram with piroxicam, celecoxib and diclofenac sodium.
Despite remarkable improvements in the speed of high performance liquid chromatography (HPLC) over the last decade, due to the development of columns containing sub-2 [micro]m particles and ultra-high performance liquid chromatography (UHPLC) instrumentation, chromatographic method development remains a significant bottleneck in many analytical laboratory workflows.