Vitamin E has
chromanol ring in its structure which donates hydrogen to free radicals thus making them unreactive (Kumari et al.
It contains extracts of avocado and soybean, hyaluronic acid, vitamin E, sodium carboxymethyl beta glucan, dimethylmethoxy
chromanol, and trimethylglycine.
Ks] channel blocker,
chromanol 293B, increased the field potential duration in control EBs, but not in patient-specific EBs.
Nifedipine (10 [micro]M) and
chromanol B (10 [micro]M) were added to the bath solution to block L-type calcium and [I.
Tocopherols and tocotrienols have a
chromanol head and a side chain at C-2 position.
Chromanol ring of tocopherols donates its phenolic hydrogen to reduce the free radical and is itself oxidised to the quinone form.
2 Both tocotrienols and tocopherols can freely donate a hydrogen atom (a proton plus electron) from the hydroxyl group on their
chromanol ring.
These compounds exert antioxidant activity by one electron reduction of the phenolic group in the
chromanol moiety.
Different numbers and positions of methyl groups present on the
chromanol head of individual molecules ("R" positions, Figure 1) distinguish each isomer by a Greek letter [alpha], [beta], [gamma]or [delta].
The term vitamin E stands for a family of eight molecules with related structures each consisting of a
chromanol ring with an alipathic side chain.
Both the tocopherol and tocotrienol groups have an aromatic
chromanol ring and differ in their side chains.
All Evitamins contain a
chromanol ring that is responsible for their free radical-scavenging abilities, due to its phenoxy group (see Fig.
