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, chromane (krō'man, -mān),
Fundamental unit of the tocopherols (vitamin E).
See also: chromanol, chromene, chromenol.
Farlex Partner Medical Dictionary © Farlex 2012
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Analysis of oxidation in aqueous and alcoholic solvents revealed that the chromane ring is broken upon oxidation, and Trolox quinone with two C=O groups is formed (Equation (12)), resulting in two electron oxidation [32]:
Trolox is formally a compound with one OH group; however, when hydrolysis of the ether bond in the chromane ring resulting in the formation of 1,4-hydroquinone is taken into the account, it is oxidized as a typical diphenolic compound (Equation (10)) with one electron exchanged per OH group.
Comments: A Chromane that protects biomolecules and cellular functions from the damage caused by the reactive species generated from air pollution or UV radiation, as well as from endogenous sources, consequently preventing the premature signs of aging.
Zuehlke, V Priti et al., "Fusarium proliferatum, an endophytic fungus from Dysoxylum binectariferum Hook.f, produces rohitukine, a chromane alkaloid possessing anti-cancer activity," Antonie van Leeuwenhoek, vol.
Under certain conditions chromane bridge structures were also detected.
In addition, cells with deleted UCP or treated with UCP inhibitors such as chromanes or genipin favor ROS generation, cyt c release, cell death, and heart failure.