Alison was nally diagnosed with Punctate Inner
Choroidopathy (PIC) after consulting experts at Birmingham's Queen Elizabeth Hospital.
Five of the most common causes are exudative macular degeneration, high/ pathological myopia, choroidal rupture, angioid streaks, and punctate inner
choroidopathy.
The differential diagnosis in leukemic patients with exudative retinal detachment includes central serous
choroidopathy, uveal effusion syndrome, choroidal neovascularization, Harada's syndrome, congenital optic disc pits.
Celiac disease and geographic (serpiginous)
choroidopathy with occurrence of thrombocytopenic purpura.
They may be large, solitary lesions, such as those seen following Toxoplasma infection, but sometimes they result in a "spotty" fundus appearance as seen in the presumed ocular histoplasmosis syndrome (POHS), birdshot chorioretinitis, multifocal choroiditis and pusctete inner
choroidopathy (PIC).
The most common cause by far is age-related macular degeneration (AMD), but other causes include myopia, choroidal inflammatory conditions such as punctate inner
choroidopathy or the presumed ocular histoplasmosis syndrome, trauma, and angioid streaks.
presumed ocular histoplasmosis syndrome (POHS) (Figure 3), punctate inner
choroidopathy (PIC)
Treatment of malignant hypertensive retinopathy,
choroidopathy and optic neuropathy consists of lowering blood pressure in a controlled manner: If the decline is too rapid there is impairment of autoregulation and this can lead to ischaemia of the optic neTve head, brain and other vital organs.
Fluorescein angiography is also an important tool in differentiating between neovascularisation attributable to AMD and that caused by other conditions such as myopia and birdshot
choroidopathy, which may require different treatment strategies.