However, since the introduction of anti-VEGF therapy, the effectiveness of anti-VEGFs against
choroidal neovascularization and the better control of intraocular pressure provided by phacoemulsification have allowed cataract surgery to be performed more safely.
Jia, "Automated
choroidal neovascularization detection algorithm for optical coherence tomography angiography," Biomedical Optics Express, vol.
Maturi et al., "Intravitreal bevacizumab for
choroidal neovascularization secondary to presumed ocular histoplasmosis syndrome," Retina, vol.
Tawansy, "Focal inner retinal hemorrhages in patients with drusen: an early sign of occult
choroidal neovascularization and chorioretinal anastomosis," Retina, vol.
Inflammatory mediators and angiogenic factors in
choroidal neovascularization: pathogenetic interactions and therapeutic implications.
AMD: Age-related macular degeneration CNV:
Choroidal neovascularization CYLD: Cylindromatosis FFA: Fundus fluorescein angiography HUVECs: Human umbilical vein endothelial cells OX-LDL: Oxidized low-density lipoprotein PDGF: Platelet-derived growth factor PEDF: Pigment epithelium-derived factors ROS: Reactive oxygen species RPE: Retinal pigment epithelium Sal A: Salvianolic acid A SFM: Serum-free medium VEGF: Vascular endothelial growth factor ZO-1: Zonula occludens-1.
Ishii et al., "Identification of a novel vascular endothelial growth factor receptor 2 inhibitor and its effect for
choroidal neovascularization in vivo," Current Eye Research, vol.
The visual outcomes following PCV are generally better compared with
choroidal neovascularization (CNV) following AMD.
GlobalData's clinical trial report, "
Choroidal Neovascularization Global Clinical Trials Review, H1, 2016" provides an overview of
Choroidal Neovascularization clinical trials scenario.
For instance, they take part in pancreatic b-cell differentiation, insulin secretion, and insulin sensitivity.17 It has been reported that microRNAs are involved in retinal and
choroidal neovascularization via down regulation of VEGF.18
The Array LaserLink device is indicated for the variety of ophthalmic uses specified for the laser to which it is attached, including diabetic retinopathy,
choroidal neovascularization, branch retinal vein occlusion, retinal tears and detachments.
Biopharmaceutical company Regeneron Pharmaceuticals (NASDAQ:REGN) revealed on Friday that ti has received European approval for EYLEA (aflibercept) Injection for the treatment of visual impairment due to myopic
choroidal neovascularization (myopic CNV), an eye disease associated with high degrees of myopia (near-sightedness).